Parkinson disease UCHL-1 gene mutations 4p14 (Q95983)
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Mutations in ubiquitin carboxyterminal hydrolase L1 (UCHL-1) lead to dysfunction of the ubiquitin proteasome system. It has been hypothesized that UCHL-1 gene mutations on chromosome 4p14 may contribute to the etiology of Parkinson's disease due to reduced removal of synuclein by proteasomes.
| Language | Label | Description | Also known as |
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| default for all languages | ID_1067231592 |
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| English | Parkinson disease UCHL-1 gene mutations 4p14 |
Mutations in ubiquitin carboxyterminal hydrolase L1 (UCHL-1) lead to dysfunction of the ubiquitin proteasome system. It has been hypothesized that UCHL-1 gene mutations on chromosome 4p14 may contribute to the etiology of Parkinson's disease due to reduced removal of synuclein by proteasomes. |
Statements
CID11:ID_1067231592
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dki-india-ID_1067231592
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Concluído
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15 August 2026
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