Chronic painful radiation-induced neuropathy (Q93996)

Chronic painful radiation-induced neuropathy is chronic pain caused by delayed local damage to the nervous system in the field of radiotherapy. It is distinct from pain caused by tumour recurrence or co-morbid disease. Pain may be the initial symptom of a neuropathy or develop over the course of the disease. The pain may be spontaneous or evoked, as an increased response to a painful stimulus (hyperalgesia) or a painful response to a normally nonpainful stimulus (allodynia). Negative (e.g., decreased or loss of sensation) and positive sensory symptoms or signs (e.g., allodynia or hyperalgesia) must be compatible with the anatomical distribution pattern of the neuropathy.