Medication-related osteonecrosis of the jaw (Q67496)

Patients may be considered to have MRONJ (medication-related osteonecrosis of the jaw) if all of the following characteristics are present: 1. Current or previous treatment with antire-sorptive or antiangiogenic agents; 2. Exposed bone or bone that can be probed through an intraoral or extraoral fistula(e) in the maxillofacial region that has persisted for more than eight weeks; 3. No history of radiation therapy to the jaws or obvious metastatic disease to the jaws.