Concentric sclerosis (Q105697)

This is a demyelinating disorder with lesion(s) of concentric bands of demyelinated and myelinated tissue. It is a variant of multiple sclerosis. Concentric sclerosis is a primary inflammatory central nervous system demyelinating disease that is considered a rare, radiographically and pathologically distinct variant of multiple sclerosis. Characterised by demyelination occurring in concentrically arranged rings of partial demyelination alternating with bands of demyelination.