Pemphigoid nodularis (Q104456)

Pemphigoid nodularis is a subtype of pemphigoid with features of both nodular prurigo and bullous pemphigoid. Patients present with pruritic nodules, papules or plaques. Blisters are usually seen at some point during the course of the disease but may also be absent. Confirming the diagnosis is often challenging but the immunopathology is similar to ordinary bullous pemphigoid. Legs are the commonly affected sites but the condition can be widespread and difficult to manage.