Primary cutaneous CD4-positive small or intermediate pleomorphic T-cell lymphoproliferative disorder (Q89594)

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This reactive lymphoproliferative disorder usually presents with a solitary plaque or tumour on the face, neck, or upper trunk. Morphologically, it is composed of small to medium-sized CD4-positive, CD8-negative, and CD30-negative pleomorphic T-lymphocytes. A small number of large pleomorphic T-lymphocytes may also be present. The lymphocytic infiltrate is dermal. Focal epidermotropism and subcutaneous involvement may be present. It has a favourable prognosis.
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    Primary cutaneous CD4-positive small or intermediate pleomorphic T-cell lymphoproliferative disorder
    This reactive lymphoproliferative disorder usually presents with a solitary plaque or tumour on the face, neck, or upper trunk. Morphologically, it is composed of small to medium-sized CD4-positive, CD8-negative, and CD30-negative pleomorphic T-lymphocytes. A small number of large pleomorphic T-lymphocytes may also be present. The lymphocytic infiltrate is dermal. Focal epidermotropism and subcutaneous involvement may be present. It has a favourable prognosis.

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