Coumarin necrosis (Q84222)
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Coumarin necrosis presents as sudden onset of severe pain and erythema in one or more localised areas of skin (typically of the breast, hip, buttock or thigh) a few days after commencing therapy with warfarin or other coumarin anticoagulant. The process may then rapidly progress to full thickness cutaneous infarction. A temporary imbalance of procoagulant and anticoagulant activity, in particular low levels of protein C, is thought to be responsible.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | ID_500349447 |
||
| English | Coumarin necrosis |
Coumarin necrosis presents as sudden onset of severe pain and erythema in one or more localised areas of skin (typically of the breast, hip, buttock or thigh) a few days after commencing therapy with warfarin or other coumarin anticoagulant. The process may then rapidly progress to full thickness cutaneous infarction. A temporary imbalance of procoagulant and anticoagulant activity, in particular low levels of protein C, is thought to be responsible. |
