{"entities":{"Q84222":{"pageid":74607,"ns":120,"title":"Item:Q84222","lastrevid":455924,"modified":"2026-08-15T09:34:53Z","type":"item","id":"Q84222","labels":{"mul":{"language":"mul","value":"ID_500349447"},"pt-br":{"language":"pt-br","value":"Necrose cumar\u00ednica"},"en":{"language":"en","value":"Coumarin necrosis"}},"descriptions":{"pt-br":{"language":"pt-br","value":"Necrose cumar\u00ednica apresenta-se como dor intensa e eritema de in\u00edcio s\u00fabito em uma ou mais \u00e1reas localizadas da pele (tipicamente mama, quadril, n\u00e1dega ou coxa) poucos dias ap\u00f3s o in\u00edcio da terapia com varfarina ou outro anticoagulante cumar\u00ednico. O processo pode, ent\u00e3o, progredir rapidamente para infarto cut\u00e2neo de espessura total. Acredita-se que um desequil\u00edbrio tempor\u00e1rio da atividade pr\u00f3-coagulante e anticoagulante, em particular n\u00edveis baixos de prote\u00edna C, seja o respons\u00e1vel."},"en":{"language":"en","value":"Coumarin necrosis presents as sudden onset of severe pain and erythema in one or more localised areas of skin (typically of the breast, hip, buttock or thigh) a few days after commencing therapy with warfarin or other coumarin anticoagulant. The process may then rapidly progress to full thickness cutaneous infarction. A temporary imbalance of procoagulant and anticoagulant activity, in particular low levels of protein C, is thought to be responsible."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"c29f0eb1ca36aac8887a4c9363c31e70ee11923d","datavalue":{"value":"https://id.who.int/icd/entity/500349447","type":"string"},"datatype":"url"},"type":"statement","id":"Q84222$004E3A37-C9BC-4A19-8E6E-0B9233DB5EE5","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"ce28f9268cacf8036d7e2b87b2f357b01af54e6c","datavalue":{"value":"CID11:ID_500349447","type":"string"},"datatype":"string"},"type":"statement","id":"Q84222$4043226D-7CB9-40B2-9EC4-E88EC7A434B1","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"e377c175b4d01dff26c220a251294ef2b1408b6d","datavalue":{"value":"dki-india-ID_500349447","type":"string"},"datatype":"string"},"type":"statement","id":"Q84222$45920B2F-ABED-473A-B768-9105E6E90922","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q84222$2B6841DE-23AE-45AD-AC9D-9E4DEB29EF33","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q84222$6895A045-8BCA-405D-9ED6-494F393D7BC9","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q84222$F0C1F24F-C805-4B5E-AD99-05309108E58E","rank":"normal"}]},"sitelinks":{}}}}