Cutaneous microvascular disturbances due to cold agglutinins (Q104325): Difference between revisions
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Crioaglutininas são imunoglobulinas IgM monoclonais ou policlonais que são capazes de aglutinar hemácias em temperaturas corporais abaixo do normal. As crioaglutininas monoclonais podem ser idiopáticas ou secundárias a doenças linfoproliferativas malignas. As crioaglutininas policlonais geralmente estão associadas a infecção, especialmente por Mycoplasma pneumoniae, mas também infecção por vírus da hepatite C, parvovírus B19 ou leptospira. Embora as crioaglutininas sejam geralmente assintomáticas, elas podem ser responsáveis por acrocianose, fenômeno de Raynaud, livedo reticular, urticária por frio e, raramente, necrose cutânea. | |||
| description / en | description / en | ||
Cold agglutinins are monoclonal or polyclonal IgM immunoglobulins which are able to agglutinate red blood cells at below normal body temperatures. Monoclonal cold agglutinins may be idiopathic or secondary to malignant lymphoproliferative diseases. Polyclonal cold agglutinins are usually associated with infection, especially Mycoplasma pneumoniae but also hepatitis C virus, parvovirus B19 or leptospiral infection. Although cold agglutinins are usually asymptomatic they may be responsible for acrocyanosis, Raynaud phenomenon, livedo reticularis, cold urticaria and, rarely, cutaneous necrosis. | |||
Revision as of 10:11, 17 August 2026
Cold agglutinins are monoclonal or polyclonal IgM immunoglobulins which are able to agglutinate red blood cells at below normal body temperatures. Monoclonal cold agglutinins may be idiopathic or secondary to malignant lymphoproliferative diseases. Polyclonal cold agglutinins are usually associated with infection, especially Mycoplasma pneumoniae but also hepatitis C virus, parvovirus B19 or leptospiral infection. Although cold agglutinins are usually asymptomatic they may be responsible for acrocyanosis, Raynaud phenomenon, livedo reticularis, cold urticaria and, rarely, cutaneous necrosis.
| Language | Label | Description | Also known as |
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| default for all languages | ID_1870120779 |
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| English | Cutaneous microvascular disturbances due to cold agglutinins |
Cold agglutinins are monoclonal or polyclonal IgM immunoglobulins which are able to agglutinate red blood cells at below normal body temperatures. Monoclonal cold agglutinins may be idiopathic or secondary to malignant lymphoproliferative diseases. Polyclonal cold agglutinins are usually associated with infection, especially Mycoplasma pneumoniae but also hepatitis C virus, parvovirus B19 or leptospiral infection. Although cold agglutinins are usually asymptomatic they may be responsible for acrocyanosis, Raynaud phenomenon, livedo reticularis, cold urticaria and, rarely, cutaneous necrosis. |
