{"entities":{"Q104325":{"pageid":94723,"ns":120,"title":"Item:Q104325","lastrevid":601194,"modified":"2026-08-17T10:11:11Z","type":"item","id":"Q104325","labels":{"mul":{"language":"mul","value":"ID_1870120779"},"pt-br":{"language":"pt-br","value":"Dist\u00farbios microvasculares cut\u00e2neos devidos a crioaglutininas"},"en":{"language":"en","value":"Cutaneous microvascular disturbances due to cold agglutinins"}},"descriptions":{"pt-br":{"language":"pt-br","value":"Crioaglutininas s\u00e3o imunoglobulinas IgM monoclonais ou policlonais que s\u00e3o capazes de aglutinar hem\u00e1cias em temperaturas corporais abaixo do normal. As crioaglutininas monoclonais podem ser idiop\u00e1ticas ou secund\u00e1rias a doen\u00e7as linfoproliferativas malignas. As crioaglutininas policlonais geralmente est\u00e3o associadas a infec\u00e7\u00e3o, especialmente por Mycoplasma pneumoniae, mas tamb\u00e9m infec\u00e7\u00e3o por v\u00edrus da hepatite C, parvov\u00edrus B19 ou leptospira. Embora as crioaglutininas sejam geralmente assintom\u00e1ticas, elas podem ser respons\u00e1veis por acrocianose, fen\u00f4meno de Raynaud, livedo reticular, urtic\u00e1ria por frio e, raramente, necrose cut\u00e2nea."},"en":{"language":"en","value":"Cold agglutinins are monoclonal or polyclonal IgM immunoglobulins which are able to agglutinate red blood cells at below normal body temperatures. Monoclonal cold agglutinins may be idiopathic or secondary to malignant lymphoproliferative diseases. Polyclonal cold agglutinins are usually associated with infection, especially Mycoplasma pneumoniae but also hepatitis C virus, parvovirus B19 or leptospiral infection. Although cold agglutinins are usually asymptomatic they may be responsible for acrocyanosis, Raynaud phenomenon, livedo reticularis, cold urticaria and, rarely, cutaneous necrosis."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"3e98421e2d05597776401746cb644eefdb8f17f9","datavalue":{"value":"https://id.who.int/icd/entity/1870120779","type":"string"},"datatype":"url"},"type":"statement","id":"Q104325$1439E827-C2FF-4F72-AC57-E8B183A69579","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"c22d128813f772eec5cad8b140467b35009626f2","datavalue":{"value":"CID11:ID_1870120779","type":"string"},"datatype":"string"},"type":"statement","id":"Q104325$DF49E5F6-F6CD-4CF7-BAB5-01C4BBAB6135","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"bbb8ab7d16a4da19079af2194731b9614c284043","datavalue":{"value":"dki-india-ID_1870120779","type":"string"},"datatype":"string"},"type":"statement","id":"Q104325$5AFFF2F4-BE97-4405-BFFC-ED368D94D643","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q104325$015BB315-F16A-4D4F-9AE3-BA9059EA7522","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q104325$1AFB297E-4242-4F0E-8AAA-1798D8C67B09","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"8612011b2ca718e4ec0db5a49d2de6d25b2e811c","datavalue":{"value":{"time":"+2026-08-16T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q104325$E89CDC75-0E7D-4861-95F4-D6A625EA1A89","rank":"normal"}]},"sitelinks":{}}}}