Scleroedema (Q96788): Difference between revisions
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O escleredema é caracterizado por enduração difusa de derme e subcutâneo normalmente afetando apenas a metade superior do corpo. A infiltração lenhosa da pele se deve tanto à infiltração do ácido hialurônico quanto ao aumento da síntese de colágeno. Histologicamente, a epiderme não é afetada, mas a derme está espessada com edema e separação de feixes de colágeno e quantidades variáveis de mucina depositada em derme profunda e subcutâneo. Existem várias formas clínicas distintas de escleredema com diferentes associações etiológicas e cursos da doença. | |||
| description / en | description / en | ||
Scleroedema is characterised by diffuse induration of the dermis and subcutis normally affecting just the upper half of the body. The woody infiltration of the skin is due both to infiltration by hyaluronan and to increased collagen synthesis. Histologically the epidermis is unaffected but the dermis is thickened with swelling and separation of collagen bundles and variable amounts of mucin deposited in the deep dermis and subcutis. There are several distinct clinical forms of scleroedema with different aetiological associations and disease courses. | |||
Revision as of 12:49, 16 August 2026
Scleroedema is characterised by diffuse induration of the dermis and subcutis normally affecting just the upper half of the body. The woody infiltration of the skin is due both to infiltration by hyaluronan and to increased collagen synthesis. Histologically the epidermis is unaffected but the dermis is thickened with swelling and separation of collagen bundles and variable amounts of mucin deposited in the deep dermis and subcutis. There are several distinct clinical forms of scleroedema with different aetiological associations and disease courses.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | ID_1549425684 |
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| English | Scleroedema |
Scleroedema is characterised by diffuse induration of the dermis and subcutis normally affecting just the upper half of the body. The woody infiltration of the skin is due both to infiltration by hyaluronan and to increased collagen synthesis. Histologically the epidermis is unaffected but the dermis is thickened with swelling and separation of collagen bundles and variable amounts of mucin deposited in the deep dermis and subcutis. There are several distinct clinical forms of scleroedema with different aetiological associations and disease courses. |
