{"entities":{"Q96788":{"pageid":87181,"ns":120,"title":"Item:Q96788","lastrevid":546645,"modified":"2026-08-16T12:49:10Z","type":"item","id":"Q96788","labels":{"mul":{"language":"mul","value":"ID_1549425684"},"pt-br":{"language":"pt-br","value":"Escleredema"},"en":{"language":"en","value":"Scleroedema"}},"descriptions":{"pt-br":{"language":"pt-br","value":"O escleredema \u00e9 caracterizado por endura\u00e7\u00e3o difusa de derme e subcut\u00e2neo normalmente afetando apenas a metade superior do corpo. A infiltra\u00e7\u00e3o lenhosa da pele se deve tanto \u00e0 infiltra\u00e7\u00e3o do \u00e1cido hialur\u00f4nico quanto ao aumento da s\u00edntese de col\u00e1geno. Histologicamente, a epiderme n\u00e3o \u00e9 afetada, mas a derme est\u00e1 espessada com edema e separa\u00e7\u00e3o de feixes de col\u00e1geno e quantidades vari\u00e1veis de mucina depositada em derme profunda e subcut\u00e2neo. Existem v\u00e1rias formas cl\u00ednicas distintas de escleredema com diferentes associa\u00e7\u00f5es etiol\u00f3gicas e cursos da doen\u00e7a."},"en":{"language":"en","value":"Scleroedema is characterised by diffuse induration of the dermis and subcutis normally affecting just the upper half of the body. The woody infiltration of the skin is due both to infiltration by hyaluronan and to increased collagen synthesis. Histologically the epidermis is unaffected but the dermis is thickened with swelling and separation of collagen bundles and variable amounts of mucin deposited in the deep dermis and subcutis. There are several distinct clinical forms of scleroedema with different aetiological associations and disease courses."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"df9f4dee0f50f6567016e789475ca9a519f2588f","datavalue":{"value":"https://id.who.int/icd/entity/1549425684","type":"string"},"datatype":"url"},"type":"statement","id":"Q96788$A1139ABD-C527-4566-AB2F-807048882313","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"11f58190cd4cb963c8d5e65171269c143fedc4b7","datavalue":{"value":"CID11:ID_1549425684","type":"string"},"datatype":"string"},"type":"statement","id":"Q96788$CA48FDEC-643A-4E41-9D88-B795DA8D9F72","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"7cf8447bd3f5387b35fcd90c40977f2e0d2c5d4e","datavalue":{"value":"dki-india-ID_1549425684","type":"string"},"datatype":"string"},"type":"statement","id":"Q96788$95D04103-03BB-49C1-9F83-F99494E94BF6","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q96788$648A3FDE-890B-4C08-B365-50A4A79BC342","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q96788$90F7B73D-BC87-48DC-83BF-8B9F097A25C0","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"378ac503ed43f21e1f461d2823a6ad59da580514","datavalue":{"value":{"time":"+2026-08-15T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q96788$600FFA22-195E-47AB-BBF9-EFDCE6147B5D","rank":"normal"}]},"sitelinks":{}}}}