Steroid sensitive nephrotic syndrome (Q92371): Difference between revisions
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Síndrome nefrótica aguda que remite dentro de 4-6 semanas com tratamento com prednisolona ou prednisona 1mg/kg/dia, máximo de 80mg (adultos), 60mg/m²/dia (crianças). Essa resposta geralmente indica glomerulonefrite de alteração mínima como o diagnóstico histológico provável._x000D_ _x000D_ Das crianças com síndrome nefrótica, 80% são responsivas a esteroides, a biópsia renal geralmente não é realizada e, portanto, o diagnóstico é baseado na resposta à terapia, apoiada pela presença de proteinúria seletiva. A mesma abordagem em adultos não é comum sem biópsia renal devido à menor frequência de remissão e à falta de confiabilidade da proteinúria seletiva como uma ferramenta diagnóstica, mas é útil na síndrome nefrótica recidivante que previamente se mostrou responsiva a esteroides, como pode ocorrer após a síndrome nefrótica da infância. | |||
| description / en | description / en | ||
Acute nephrotic syndrome which resolves within 4-6 weeks on treatment with prednisolone or prednisone 1mg/kg/day, maximum 80mg for (adults), 60mg/m²/day (children).This response usually indicates minimal change glomerulonephritis as the likely histological diagnosis. Of children with nephrotic syndrome 80% are steroid responsive, renal biopsy is not usually performed and thus the diagnosis is based on response to therapy, supported by the presence of selective proteinuria. The same approach in adults is not usual without renal biopsy due to the lower frequency of remission and the lack of reliability of selective proteinuria as a diagnostic tool, but is useful in relapsing nephrotic syndrome previously shown to be previously steroid responsive as might occur after childhood nephrotic syndrome. | |||
Revision as of 07:31, 16 August 2026
Acute nephrotic syndrome which resolves within 4-6 weeks on treatment with prednisolone or prednisone 1mg/kg/day, maximum 80mg for (adults), 60mg/m²/day (children).This response usually indicates minimal change glomerulonephritis as the likely histological diagnosis. Of children with nephrotic syndrome 80% are steroid responsive, renal biopsy is not usually performed and thus the diagnosis is based on response to therapy, supported by the presence of selective proteinuria. The same approach in adults is not usual without renal biopsy due to the lower frequency of remission and the lack of reliability of selective proteinuria as a diagnostic tool, but is useful in relapsing nephrotic syndrome previously shown to be previously steroid responsive as might occur after childhood nephrotic syndrome.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | ID_1426920554 |
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| English | Steroid sensitive nephrotic syndrome |
Acute nephrotic syndrome which resolves within 4-6 weeks on treatment with prednisolone or prednisone 1mg/kg/day, maximum 80mg for (adults), 60mg/m²/day (children).This response usually indicates minimal change glomerulonephritis as the likely histological diagnosis. Of children with nephrotic syndrome 80% are steroid responsive, renal biopsy is not usually performed and thus the diagnosis is based on response to therapy, supported by the presence of selective proteinuria. The same approach in adults is not usual without renal biopsy due to the lower frequency of remission and the lack of reliability of selective proteinuria as a diagnostic tool, but is useful in relapsing nephrotic syndrome previously shown to be previously steroid responsive as might occur after childhood nephrotic syndrome. |
