{"entities":{"Q92371":{"pageid":82764,"ns":120,"title":"Item:Q92371","lastrevid":514667,"modified":"2026-08-16T07:31:03Z","type":"item","id":"Q92371","labels":{"mul":{"language":"mul","value":"ID_1426920554"},"pt-br":{"language":"pt-br","value":"S\u00edndrome nefr\u00f3tica sens\u00edvel a esteroides"},"en":{"language":"en","value":"Steroid sensitive nephrotic syndrome"}},"descriptions":{"pt-br":{"language":"pt-br","value":"S\u00edndrome nefr\u00f3tica aguda que remite dentro de 4-6 semanas com tratamento com prednisolona ou prednisona 1mg/kg/dia, m\u00e1ximo de 80mg (adultos), 60mg/m\u00b2/dia (crian\u00e7as). Essa resposta geralmente indica glomerulonefrite de altera\u00e7\u00e3o m\u00ednima como o diagn\u00f3stico histol\u00f3gico prov\u00e1vel._x000D_ _x000D_ Das crian\u00e7as com s\u00edndrome nefr\u00f3tica, 80% s\u00e3o responsivas a esteroides, a bi\u00f3psia renal geralmente n\u00e3o \u00e9 realizada e, portanto, o diagn\u00f3stico \u00e9 baseado na resposta \u00e0 terapia, apoiada pela presen\u00e7a de protein\u00faria seletiva. A mesma abordagem em adultos n\u00e3o \u00e9 comum sem bi\u00f3psia renal devido \u00e0 menor frequ\u00eancia de remiss\u00e3o e \u00e0 falta de confiabilidade da protein\u00faria seletiva como uma ferramenta diagn\u00f3stica, mas \u00e9 \u00fatil na s\u00edndrome nefr\u00f3tica recidivante que previamente se mostrou responsiva a esteroides, como pode ocorrer ap\u00f3s a s\u00edndrome nefr\u00f3tica da inf\u00e2ncia."},"en":{"language":"en","value":"Acute nephrotic syndrome which resolves within 4-6 weeks on treatment with prednisolone or prednisone 1mg/kg/day, maximum 80mg for (adults), 60mg/m\u00b2/day (children).This response usually indicates minimal change glomerulonephritis as the likely histological diagnosis.  Of children with nephrotic syndrome 80% are steroid responsive, renal biopsy is not usually performed and thus the diagnosis is based on response to therapy, supported by the presence of selective proteinuria. The same approach in adults is not usual without renal biopsy due to the lower frequency of remission and the lack of reliability of selective proteinuria as a diagnostic tool, but is useful in relapsing nephrotic syndrome previously shown to be previously steroid responsive as might occur after childhood nephrotic syndrome."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"ac7f0b44c759139b76cef98195771941d05232e6","datavalue":{"value":"https://id.who.int/icd/entity/1426920554","type":"string"},"datatype":"url"},"type":"statement","id":"Q92371$FCA33ABC-D8FA-4E2C-B1EF-5DDE563BCB03","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"1757139e8c18ddab8cc7e3188f67a916aaa5e41a","datavalue":{"value":"CID11:ID_1426920554","type":"string"},"datatype":"string"},"type":"statement","id":"Q92371$E50852D8-FC11-4395-8D0B-9339635904EF","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"f5bc478412808c8e286677b56b127c1e17f689ec","datavalue":{"value":"dki-india-ID_1426920554","type":"string"},"datatype":"string"},"type":"statement","id":"Q92371$F9CA03F1-5048-4626-842B-AD9997C4B9F4","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q92371$F3B96854-C9ED-4BA3-8050-61492CF43D18","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q92371$34DF6F00-E3DD-403E-85D0-98F34B569813","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"378ac503ed43f21e1f461d2823a6ad59da580514","datavalue":{"value":{"time":"+2026-08-15T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q92371$8A8F02D7-FF3F-4F4D-850B-7E3E10C4AB20","rank":"normal"}]},"sitelinks":{}}}}