Parkinsonism (Q49459): Difference between revisions
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Parkinsonismo é uma síndrome clínica caracterizada por quatro manifestações cardinais: tremor em repouso, rigidez muscular, acinesia ou bradicinesia e distúrbios posturais que incluem marcha arrastada, postura fletida e perda de reflexos posturais. Bradicinesia e uma outra manifestação clínica são exigidas para fazer o diagnóstico de parkinsonismo. Parkinsonismo pode resultar de uma variedade de condições que incluem transtornos neurodegenerativos progressivos como Doença de Parkinson e Parkinsonismo atípico em que a degeneração progressiva da substância negra e de outros neurônios leva a deficiência dopaminérgica. Parkinsonismo pode também resultar de lesões estruturais como acidentes vasculares cerebrais ou tumores ou bloqueio de receptores dopaminérgicos no estriado por drogas como os neurolépticos. | |||
| description / en | description / en | ||
Parkinsonism is a clinical syndrome characterised by four cardinal features: rest tremor, muscular rigidity, akinesia or bradykinesia, and postural disturbances which include shuffling gait and flexed posture and loss of postural reflexes. Bradykinesia and one other clinical feature is required to make a diagnosis of Parkinsonism. Parkinsonism may result from a variety of conditions including progressive neurodegenerative disorders such as Parkinson Disease or Atypical Parkinsonism where the progressive degeneration of nigral and other neurons leads to dopamine deficiency. Parkinsonism may also be a result of structural lesions such as strokes or tumours or blockage of dopamine receptors in the striatum by drugs such as neuroleptics. | |||
Revision as of 19:50, 13 August 2026
Parkinsonism is a clinical syndrome characterised by four cardinal features: rest tremor, muscular rigidity, akinesia or bradykinesia, and postural disturbances which include shuffling gait and flexed posture and loss of postural reflexes. Bradykinesia and one other clinical feature is required to make a diagnosis of Parkinsonism. Parkinsonism may result from a variety of conditions including progressive neurodegenerative disorders such as Parkinson Disease or Atypical Parkinsonism where the progressive degeneration of nigral and other neurons leads to dopamine deficiency. Parkinsonism may also be a result of structural lesions such as strokes or tumours or blockage of dopamine receptors in the striatum by drugs such as neuroleptics.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | 8A00 |
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| English | Parkinsonism |
Parkinsonism is a clinical syndrome characterised by four cardinal features: rest tremor, muscular rigidity, akinesia or bradykinesia, and postural disturbances which include shuffling gait and flexed posture and loss of postural reflexes. Bradykinesia and one other clinical feature is required to make a diagnosis of Parkinsonism. Parkinsonism may result from a variety of conditions including progressive neurodegenerative disorders such as Parkinson Disease or Atypical Parkinsonism where the progressive degeneration of nigral and other neurons leads to dopamine deficiency. Parkinsonism may also be a result of structural lesions such as strokes or tumours or blockage of dopamine receptors in the striatum by drugs such as neuroleptics. |
