Sickle cell thalassaemia with crisis with fever (Q92039): Difference between revisions

A disease caused by genetically inherited sickle cell (HbS) mutation from one parent and a thalassemia mutation from the other parent. This disease is characterised by abnormal rigid sickle-shaped red blood cells and abnormal production of the beta chain in a haemoglobin molecule, crisis and, fever. This disease may present with pallor, jaundice, fever, iron overload, fatigue, or shortness of breath. Confirmation is by identification of mutations through genetic testing.