Autoimmune encephalitis (Q84119): Difference between revisions
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A encefalite autoimune é uma doença inflamatória imunomediada do sistema nervoso central. A apresentação é subaguda com dificuldades cognitivas flutuantes (particularmente memória de curto prazo). Uma história pessoal / familiar de autoimunidade é típica e as investigações podem revelar anormalidades de ressonância magnética do lobo temporal mesial e um fluido cefalorraquiano inflamatório. Podem ser encontrados autoanticorpos neurais (por exemplo, autoanticorpos complexos de canal de potássio controlados por voltagem) e não órgão-específicos (anticorpos de peroxidase da tireoide [TPO]). A exclusão de etiologias alternativas (por exemplo, infecções) é importante. A resposta à imunoterapia pode ser usada para confirmar o diagnóstico. | |||
| description / en | description / en | ||
Autoimmune encephalitis is an immune mediated inflammatory disorder of the central nervous system. Presentation is subacute with fluctuating cognitive difficulties (particularly short-term memory). A personal/family history of autoimmunity is typical and investigations may reveal mesial temporal lobe MRI abnormalities and an inflammatory spinal fluid. Accompanying neural autoantibodies (e.g. voltage gated potassium channel complex autoantibodies) and non-organ specific (thyroid peroxidase [TPO] antibodies) may be found. Exclusion of alternative etiologies (e.g. infections) is important. Response to immunotherapy may be used to confirm the diagnosis. | |||
Revision as of 09:28, 15 August 2026
Autoimmune encephalitis is an immune mediated inflammatory disorder of the central nervous system. Presentation is subacute with fluctuating cognitive difficulties (particularly short-term memory). A personal/family history of autoimmunity is typical and investigations may reveal mesial temporal lobe MRI abnormalities and an inflammatory spinal fluid. Accompanying neural autoantibodies (e.g. voltage gated potassium channel complex autoantibodies) and non-organ specific (thyroid peroxidase [TPO] antibodies) may be found. Exclusion of alternative etiologies (e.g. infections) is important. Response to immunotherapy may be used to confirm the diagnosis.
| Language | Label | Description | Also known as |
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| default for all languages | ID_241281019 |
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| English | Autoimmune encephalitis |
Autoimmune encephalitis is an immune mediated inflammatory disorder of the central nervous system. Presentation is subacute with fluctuating cognitive difficulties (particularly short-term memory). A personal/family history of autoimmunity is typical and investigations may reveal mesial temporal lobe MRI abnormalities and an inflammatory spinal fluid. Accompanying neural autoantibodies (e.g. voltage gated potassium channel complex autoantibodies) and non-organ specific (thyroid peroxidase [TPO] antibodies) may be found. Exclusion of alternative etiologies (e.g. infections) is important. Response to immunotherapy may be used to confirm the diagnosis. |
