{"entities":{"Q84119":{"pageid":74504,"ns":120,"title":"Item:Q84119","lastrevid":455168,"modified":"2026-08-15T09:28:59Z","type":"item","id":"Q84119","labels":{"mul":{"language":"mul","value":"ID_241281019"},"pt-br":{"language":"pt-br","value":"Encefalite autoimune"},"en":{"language":"en","value":"Autoimmune encephalitis"}},"descriptions":{"pt-br":{"language":"pt-br","value":"A encefalite autoimune \u00e9 uma doen\u00e7a inflamat\u00f3ria imunomediada do sistema nervoso central. A apresenta\u00e7\u00e3o \u00e9 subaguda com dificuldades cognitivas flutuantes (particularmente mem\u00f3ria de curto prazo). Uma hist\u00f3ria pessoal / familiar de autoimunidade \u00e9 t\u00edpica e as investiga\u00e7\u00f5es podem revelar anormalidades de resson\u00e2ncia magn\u00e9tica do lobo temporal mesial e um fluido cefalorraquiano inflamat\u00f3rio. Podem ser encontrados autoanticorpos neurais (por exemplo, autoanticorpos complexos de canal de pot\u00e1ssio controlados por voltagem) e n\u00e3o \u00f3rg\u00e3o-espec\u00edficos (anticorpos de peroxidase da tireoide [TPO]). A exclus\u00e3o de etiologias alternativas (por exemplo, infec\u00e7\u00f5es) \u00e9 importante. A resposta \u00e0 imunoterapia pode ser usada para confirmar o diagn\u00f3stico."},"en":{"language":"en","value":"Autoimmune encephalitis is an immune mediated inflammatory disorder of the central nervous system. Presentation is subacute with fluctuating cognitive difficulties (particularly short-term memory). A personal/family history of autoimmunity is typical and investigations may reveal mesial temporal lobe MRI abnormalities and an inflammatory spinal fluid. Accompanying neural autoantibodies (e.g. voltage gated potassium channel complex autoantibodies) and non-organ specific (thyroid peroxidase [TPO] antibodies) may be found. Exclusion of alternative etiologies (e.g. infections) is important. Response to immunotherapy may be used to confirm the diagnosis."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"6353cfede8982faeb7123c02c0ed6ca92b371320","datavalue":{"value":"https://id.who.int/icd/entity/241281019","type":"string"},"datatype":"url"},"type":"statement","id":"Q84119$2302E5B8-635B-46A5-9B2A-BEE6A349704B","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"2ce5df81ad61afb9a9b305823dc57842543acb74","datavalue":{"value":"CID11:ID_241281019","type":"string"},"datatype":"string"},"type":"statement","id":"Q84119$5F65CEB2-074B-49E8-ADC8-E95AFEC01711","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"b2381ca5292a4eb36a9f7736c2fc5783537f2405","datavalue":{"value":"dki-india-ID_241281019","type":"string"},"datatype":"string"},"type":"statement","id":"Q84119$81002B03-BD18-418D-8B6C-6AF72558A247","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q84119$1F0053C2-981E-4845-9DA7-5701946A882D","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q84119$A33D1D4E-6221-4BC4-AA2A-AACE3C944517","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q84119$F1E74A19-0E2D-433F-8380-EB70FDBCD66E","rank":"normal"}]},"sitelinks":{}}}}