Meningitis due to Cryptococcus neoformans (Q38434): Difference between revisions
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Inflamação da pia e aracnoide e do líquido espinal associada ao fungo Cryptococcus neoformans. O trato respiratório é a porta de entrada usual e a meningite pode ocorrer após a disseminação dos pulmões para as meninges. A meningite por C. neoforman tende a ocorrer em pacientes com imunidade celular alterada. As meningites geralmente evoluem de forma subaguda, mas podem ser agudas. As características clínicas incluem cefaleia, febre, náuseas e vômitos, meningismo, distúrbios visuais, estado mental anormal, convulsões e pressão intracraniana elevada. Dor de cabeça, febre e torcicolo podem estar ausentes. O diagnóstico é feito por exame microscópico do líquido espinal, cultura de LCR e sangue, e teste de aglutinação em látex para detecção do antígeno polissacarídeo capsular no LCR e no sangue. O organismo pode ser visto na coloração de Gram ou tinta nanquim do LCR. O líquido espinal geralmente mostra pleocitose linfocítica variável, baixo teor de glicose e alto nível de proteína. | |||
| description / en | description / en | ||
Inflammation of the pia and arachnoid and spinal fluid associated with the fungus cryptococcus neoformans. The respiratory tract is the usual portal of entry and meningitis may occur after dissemination to the meninges from the lungs. C. neoformans meningitis tends to occur in patients with defective cellular immunity. The meningitis usually evolves subacutely, but may be acute. Clinical features include headache, fever, nausea and vomiting, meningismus, visual disturbances, abnormal mental status, seizures, and raised intracranial pressure. Headache, fever, and stiff neck may be absent. The diagnosis is made by microscopic examination of the spinal fluid, culture of CSF and blood, and the latex agglutination test to detect the capsular polysaccharide antigen in CSF and blood. The organism may be seen on Gram stain or India ink stain of the CSF. The spinal fluid usually shows varuable lymphocytic pleocytosis, a low glucose content, and a high protein level. | |||
Revision as of 03:28, 13 August 2026
Inflammation of the pia and arachnoid and spinal fluid associated with the fungus cryptococcus neoformans. The respiratory tract is the usual portal of entry and meningitis may occur after dissemination to the meninges from the lungs. C. neoformans meningitis tends to occur in patients with defective cellular immunity. The meningitis usually evolves subacutely, but may be acute. Clinical features include headache, fever, nausea and vomiting, meningismus, visual disturbances, abnormal mental status, seizures, and raised intracranial pressure. Headache, fever, and stiff neck may be absent. The diagnosis is made by microscopic examination of the spinal fluid, culture of CSF and blood, and the latex agglutination test to detect the capsular polysaccharide antigen in CSF and blood. The organism may be seen on Gram stain or India ink stain of the CSF. The spinal fluid usually shows varuable lymphocytic pleocytosis, a low glucose content, and a high protein level.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | 1F27.10 |
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| English | Meningitis due to Cryptococcus neoformans |
Inflammation of the pia and arachnoid and spinal fluid associated with the fungus cryptococcus neoformans. The respiratory tract is the usual portal of entry and meningitis may occur after dissemination to the meninges from the lungs. C. neoformans meningitis tends to occur in patients with defective cellular immunity. The meningitis usually evolves subacutely, but may be acute. Clinical features include headache, fever, nausea and vomiting, meningismus, visual disturbances, abnormal mental status, seizures, and raised intracranial pressure. Headache, fever, and stiff neck may be absent. The diagnosis is made by microscopic examination of the spinal fluid, culture of CSF and blood, and the latex agglutination test to detect the capsular polysaccharide antigen in CSF and blood. The organism may be seen on Gram stain or India ink stain of the CSF. The spinal fluid usually shows varuable lymphocytic pleocytosis, a low glucose content, and a high protein level. |
