{"entities":{"Q38434":{"pageid":28800,"ns":120,"title":"Item:Q38434","lastrevid":112565,"modified":"2026-08-13T03:28:36Z","type":"item","id":"Q38434","labels":{"mul":{"language":"mul","value":"1F27.10"},"pt-br":{"language":"pt-br","value":"Meningite por Cryptococcus neoformans"},"en":{"language":"en","value":"Meningitis due to Cryptococcus neoformans"}},"descriptions":{"pt-br":{"language":"pt-br","value":"Inflama\u00e7\u00e3o da pia e aracnoide e do l\u00edquido espinal associada ao fungo Cryptococcus neoformans. O trato respirat\u00f3rio \u00e9 a porta de entrada usual e a meningite pode ocorrer ap\u00f3s a dissemina\u00e7\u00e3o dos pulm\u00f5es para as meninges. A meningite por C. neoforman tende a ocorrer em pacientes com imunidade celular alterada. As meningites geralmente evoluem de forma subaguda, mas podem ser agudas. As caracter\u00edsticas cl\u00ednicas incluem cefaleia, febre, n\u00e1useas e v\u00f4mitos, meningismo, dist\u00farbios visuais, estado mental anormal, convuls\u00f5es e press\u00e3o intracraniana elevada. Dor de cabe\u00e7a, febre e torcicolo podem estar ausentes. O diagn\u00f3stico \u00e9 feito por exame microsc\u00f3pico do l\u00edquido espinal, cultura de LCR e sangue, e teste de aglutina\u00e7\u00e3o em l\u00e1tex para detec\u00e7\u00e3o do ant\u00edgeno polissacar\u00eddeo capsular no LCR e no sangue. O organismo pode ser visto na colora\u00e7\u00e3o de Gram ou tinta nanquim do LCR. O l\u00edquido espinal geralmente mostra pleocitose linfoc\u00edtica vari\u00e1vel, baixo teor de glicose e alto n\u00edvel de prote\u00edna."},"en":{"language":"en","value":"Inflammation of the pia and arachnoid and spinal fluid associated with the fungus cryptococcus neoformans. The respiratory tract is the usual portal of entry and meningitis may occur after dissemination to the meninges from the lungs. C. neoformans meningitis tends to occur in patients with defective cellular immunity. The meningitis usually evolves subacutely, but may be acute. Clinical features include headache, fever, nausea and vomiting, meningismus, visual disturbances, abnormal mental status, seizures, and raised intracranial pressure. Headache, fever, and stiff neck may be absent. The diagnosis is made by microscopic examination of the spinal fluid, culture of CSF and blood, and the latex agglutination test to detect the capsular polysaccharide antigen in CSF and blood. The organism may be seen on Gram stain or India ink stain of the CSF. The spinal fluid usually shows varuable lymphocytic pleocytosis, a low glucose content, and a high protein level."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"0f7c678ad10dc7effda594434fb66dab84e0c14e","datavalue":{"value":"https://id.who.int/icd/entity/738912364","type":"string"},"datatype":"url"},"type":"statement","id":"Q38434$910351E5-A838-4D32-A34F-DF3D16ED4F73","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"181b7dea0806faae6d65e822eac8f079326b7428","datavalue":{"value":"CID11:1F27.10","type":"string"},"datatype":"string"},"type":"statement","id":"Q38434$BF621251-28BE-4990-B7FA-4460D75CDDAB","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"b4592352d2cb5058ffc349f6819f102717e4f3a4","datavalue":{"value":"dki-india-1F27.10","type":"string"},"datatype":"string"},"type":"statement","id":"Q38434$F53EE026-81C5-42F7-883D-C8619F9E4ECB","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q38434$E211589E-0EA3-46D1-A3F9-538FE24187AF","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q38434$75C5B8F5-1CDD-4C39-9B58-E2FC7AAA7FFC","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q38434$F82E8837-E088-43BB-9897-3A9357D306E5","rank":"normal"}],"P89":[{"mainsnak":{"snaktype":"value","property":"P89","hash":"19001dcad509f59cf7392b0fc116c6d58e8c06f3","datavalue":{"value":{"entity-type":"item","numeric-id":12423,"id":"Q12423"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q38434$EFFF6A20-138D-409D-97AF-7991DDA52D3A","rank":"normal"}]},"sitelinks":{}}}}