Paraneoplastic opsoclonus myoclonus (Q100589): Difference between revisions
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CID11:ID_2088074552 | |||||||||||||||
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15 August 2026
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Latest revision as of 17:18, 16 August 2026
Paraneoplastic opsoclonus myoclonus (OM) results from a targeted attack on the brainstem as a consequence of a potentially effective tumour immune response initiated by onco-neural antigens derived from a systemic cancer. In children the cancer is almost always neuroblastoma, while in adults a variety of cancers may be detected but small-cell lung cancers and breast cancers are most common. In adults paraneoplastic OM it is often associated with the neural autoantibody anti-neuronal nuclear antibody type 2 [ANNA-2 or anti-Ri], but other neural autoantibodies may also accompany OM. Associated autoantibodies: ANNA-2(anti-Ri) (antineuronal nuclear autoantibody type 2); NMDA-R (N-methyl-D-aspartate receptor autoantibodies).
| Language | Label | Description | Also known as |
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| default for all languages | ID_2088074552 |
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| English | Paraneoplastic opsoclonus myoclonus |
Paraneoplastic opsoclonus myoclonus (OM) results from a targeted attack on the brainstem as a consequence of a potentially effective tumour immune response initiated by onco-neural antigens derived from a systemic cancer. In children the cancer is almost always neuroblastoma, while in adults a variety of cancers may be detected but small-cell lung cancers and breast cancers are most common. In adults paraneoplastic OM it is often associated with the neural autoantibody anti-neuronal nuclear antibody type 2 [ANNA-2 or anti-Ri], but other neural autoantibodies may also accompany OM. Associated autoantibodies: ANNA-2(anti-Ri) (antineuronal nuclear autoantibody type 2); NMDA-R (N-methyl-D-aspartate receptor autoantibodies). |
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CID11:ID_2088074552
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dki-india-ID_2088074552
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Concluído
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15 August 2026
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