Scleroedema (Q96788): Difference between revisions

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Timezone +00:00
Calendar Gregorian
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Latest revision as of 12:49, 16 August 2026

Scleroedema is characterised by diffuse induration of the dermis and subcutis normally affecting just the upper half of the body. The woody infiltration of the skin is due both to infiltration by hyaluronan and to increased collagen synthesis. Histologically the epidermis is unaffected but the dermis is thickened with swelling and separation of collagen bundles and variable amounts of mucin deposited in the deep dermis and subcutis. There are several distinct clinical forms of scleroedema with different aetiological associations and disease courses.

Language	Label	Description	Also known as
default for all languages	ID_1549425684
English	Scleroedema	Scleroedema is characterised by diffuse induration of the dermis and subcutis normally affecting just the upper half of the body. The woody infiltration of the skin is due both to infiltration by hyaluronan and to increased collagen synthesis. Histologically the epidermis is unaffected but the dermis is thickened with swelling and separation of collagen bundles and variable amounts of mucin deposited in the deep dermis and subcutis. There are several distinct clinical forms of scleroedema with different aetiological associations and disease courses.