Coumarin necrosis (Q84222): Difference between revisions
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Necrose cumarínica apresenta-se como dor intensa e eritema de início súbito em uma ou mais áreas localizadas da pele (tipicamente mama, quadril, nádega ou coxa) poucos dias após o início da terapia com varfarina ou outro anticoagulante cumarínico. O processo pode, então, progredir rapidamente para infarto cutâneo de espessura total. Acredita-se que um desequilíbrio temporário da atividade pró-coagulante e anticoagulante, em particular níveis baixos de proteína C, seja o responsável. | |||||||||||||||
| description / en | description / en | ||||||||||||||
Coumarin necrosis presents as sudden onset of severe pain and erythema in one or more localised areas of skin (typically of the breast, hip, buttock or thigh) a few days after commencing therapy with warfarin or other coumarin anticoagulant. The process may then rapidly progress to full thickness cutaneous infarction. A temporary imbalance of procoagulant and anticoagulant activity, in particular low levels of protein C, is thought to be responsible. | |||||||||||||||
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| Property / Canonical URI: https://id.who.int/icd/entity/500349447 / rank | |||||||||||||||
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CID11:ID_500349447 | |||||||||||||||
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dki-india-ID_500349447 | |||||||||||||||
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| Property / Verification Status: Concluído / rank | |||||||||||||||
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| Property / Knowledge Architect: https://pauloleads.com.br/cases-publicos/ / rank | |||||||||||||||
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13 August 2026
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| Property / Collection date: 13 August 2026 / rank | |||||||||||||||
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Latest revision as of 09:34, 15 August 2026
Coumarin necrosis presents as sudden onset of severe pain and erythema in one or more localised areas of skin (typically of the breast, hip, buttock or thigh) a few days after commencing therapy with warfarin or other coumarin anticoagulant. The process may then rapidly progress to full thickness cutaneous infarction. A temporary imbalance of procoagulant and anticoagulant activity, in particular low levels of protein C, is thought to be responsible.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | ID_500349447 |
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| English | Coumarin necrosis |
Coumarin necrosis presents as sudden onset of severe pain and erythema in one or more localised areas of skin (typically of the breast, hip, buttock or thigh) a few days after commencing therapy with warfarin or other coumarin anticoagulant. The process may then rapidly progress to full thickness cutaneous infarction. A temporary imbalance of procoagulant and anticoagulant activity, in particular low levels of protein C, is thought to be responsible. |
Statements
CID11:ID_500349447
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dki-india-ID_500349447
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Concluído
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13 August 2026
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