Autoimmune necrotising myopathy (Q84062): Difference between revisions

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Latest revision as of 09:25, 15 August 2026

Presents with proximal muscle weakness occurring during or after treatment with statins; often associated with elevated serum creatine kinase (CK). The muscle weakness can persist, after discontinuation of statin treatment. Neuropathologically gives evidence of necrotizing myopathy with scarce inflammation. Immune suppressive therapy may be needed. Associated neural autoantibodies are Anti- SRP (signal recognition particle antibody) and anti HMGCR (Autoantibodies recognizing 3-hydroxy-3-methylglutaryl-coenzyme A reductase)

Language	Label	Description	Also known as
default for all languages	ID_1655474050
English	Autoimmune necrotising myopathy	Presents with proximal muscle weakness occurring during or after treatment with statins; often associated with elevated serum creatine kinase (CK). The muscle weakness can persist, after discontinuation of statin treatment. Neuropathologically gives evidence of necrotizing myopathy with scarce inflammation. Immune suppressive therapy may be needed. Associated neural autoantibodies are Anti- SRP (signal recognition particle antibody) and anti HMGCR (Autoantibodies recognizing 3-hydroxy-3-methylglutaryl-coenzyme A reductase)