Parkinson disease UCHL-1 gene mutations 4p14 (Q95983): Difference between revisions

@@ description / pt-br / description / pt-br @@
+Mutações na hidrolase carboxiterminal da ubiquitina L1 (UCHL-1) levam à disfunção do sistema proteassoma da ubiquitina. Foi levantada a hipótese de que mutações no gene UCHL-1 no cromossomo 4p14 podem contribuir para a etiologia da doença de Parkinson devido à redução da remoção de sinucleína pelos proteassomas.
@@ description / en / description / en @@
+Mutations in ubiquitin carboxyterminal hydrolase L1 (UCHL-1) lead to dysfunction of the ubiquitin proteasome system. It has been hypothesized that UCHL-1 gene mutations on chromosome 4p14 may contribute to the etiology of Parkinson's disease due to reduced removal of synuclein by proteasomes.
@@ Property / Canonical URI @@
+https://id.who.int/icd/entity/1067231592
@@ Property / Canonical URI: https://id.who.int/icd/entity/1067231592 / rank @@
+Normal rank
@@ Property / CURIE @@
+CID11:ID_1067231592
@@ Property / CURIE: CID11:ID_1067231592 / rank @@
+Normal rank
@@ Property / Canary Token @@
+dki-india-ID_1067231592
@@ Property / Canary Token: dki-india-ID_1067231592 / rank @@
+Normal rank
@@ Property / Verification Status @@
+Concluído
@@ Property / Verification Status: Concluído / rank @@
+Normal rank
@@ Property / Knowledge Architect @@
+https://pauloleads.com.br/cases-publicos/
+Normal rank
@@ Property / Collection date @@
+August 2026Timestamp +2026-08-15T00:00:00Z
Timezone +00:00
Calendar Gregorian
Precision 1 day
Before 0
After 0
-Timestamp
++2026-08-15T00:00:00Z
-Timezone
++00:00
-Calendar
+Gregorian
-Precision
+day
 Before
 After
@@ Property / Collection date: 15 August 2026 / rank @@
+Normal rank

Latest revision as of 11:49, 16 August 2026

Mutations in ubiquitin carboxyterminal hydrolase L1 (UCHL-1) lead to dysfunction of the ubiquitin proteasome system. It has been hypothesized that UCHL-1 gene mutations on chromosome 4p14 may contribute to the etiology of Parkinson's disease due to reduced removal of synuclein by proteasomes.

Language	Label	Description	Also known as
default for all languages	ID_1067231592
English	Parkinson disease UCHL-1 gene mutations 4p14	Mutations in ubiquitin carboxyterminal hydrolase L1 (UCHL-1) lead to dysfunction of the ubiquitin proteasome system. It has been hypothesized that UCHL-1 gene mutations on chromosome 4p14 may contribute to the etiology of Parkinson's disease due to reduced removal of synuclein by proteasomes.