{"entities":{"Q99665":{"pageid":90058,"ns":120,"title":"Item:Q99665","lastrevid":567428,"modified":"2026-08-16T16:20:29Z","type":"item","id":"Q99665","labels":{"mul":{"language":"mul","value":"ID_278069977"},"pt-br":{"language":"pt-br","value":"Coreoacantocitose"},"en":{"language":"en","value":"Choreoacanthocytosis"}},"descriptions":{"pt-br":{"language":"pt-br","value":"A coreia-acantocitose \u00e9 uma forma de neuroacantocitose que \u00e9 caracterizada clinicamente por um fen\u00f3tipo semelhante \u00e0 doen\u00e7a de Huntington com sintomas neurol\u00f3gicos progressivos, incluindo transtornos do movimento, manifesta\u00e7\u00f5es psiqui\u00e1tricas e dist\u00farbios cognitivos. Esses pacientes freq\u00fcentemente apresentam distonia alimentar. A core\u00edna dos gl\u00f3bulos vermelhos est\u00e1 ausente e uma muta\u00e7\u00e3o no gene CHAC \u00e9 freq\u00fcentemente a respons\u00e1vel. CK (creatina quinase) geralmente est\u00e1 aumentada e os pacientes podem apresentar neuropatia."},"en":{"language":"en","value":"Chorea-acanthocytosis is a form of neuroacanthocytosis and is characterized clinically by a Huntington disease-like phenotype with progressive neurological symptoms including movement disorders, psychiatric manifestations and cognitive disturbances. These patients often exhibit feeding dystonia. The red cell chorein is absent and a mutation is CHAC gene is often responsible. CK (Creatine kinase) is often raised and patients may have neuropathy."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"2ce9d7f10740aa447bf194edcfe4ea60a2fa435f","datavalue":{"value":"https://id.who.int/icd/entity/278069977","type":"string"},"datatype":"url"},"type":"statement","id":"Q99665$941A684D-3CAB-4F18-8AB1-EC62FF3A7A78","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"c1aa2054956e21e75dfbdccd575cd3eb4306e8f6","datavalue":{"value":"CID11:ID_278069977","type":"string"},"datatype":"string"},"type":"statement","id":"Q99665$8A396B6D-1F6B-49D9-9E58-9518A74782C3","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"18c132ba3fe92100a6c98a8b206a18e90018d6a4","datavalue":{"value":"dki-india-ID_278069977","type":"string"},"datatype":"string"},"type":"statement","id":"Q99665$1A4D7820-C663-46DB-8035-E9B452F431B1","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q99665$17AE38D9-D8B7-4CBE-BA2B-FE62B9B89962","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q99665$24CC6C70-1476-44D9-8725-310EC0CA1CE6","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"378ac503ed43f21e1f461d2823a6ad59da580514","datavalue":{"value":{"time":"+2026-08-15T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q99665$978898E0-3181-448B-8CB9-5472593DB088","rank":"normal"}]},"sitelinks":{}}}}