{"entities":{"Q98421":{"pageid":88814,"ns":120,"title":"Item:Q98421","lastrevid":558444,"modified":"2026-08-16T14:52:27Z","type":"item","id":"Q98421","labels":{"mul":{"language":"mul","value":"ID_2104488268"},"pt-br":{"language":"pt-br","value":"Hiperlipoproteinemia tipo 1"},"en":{"language":"en","value":"Hyperlipoproteinaemia type 1"}},"descriptions":{"pt-br":{"language":"pt-br","value":"A hiperlipoproteinemia tipo I existe em v\u00e1rias formas: Defici\u00eancia de lipoprote\u00edna lipase (Tipo Ia), devido a uma defici\u00eancia de lipoprote\u00edna lipase ou apolipoprote\u00edna C2 alterada, resultando em aumento de quilom\u00edcrons, as part\u00edculas que transferem \u00e1cidos graxos do trato digestivo para o f\u00edgado. Defici\u00eancia familiar de apoprote\u00edna CII (Tipo Ib), uma condi\u00e7\u00e3o causada pela falta de ativador da lipoprote\u00edna lipase . Quilomicronemia devido ao inibidor circulante da lipoprote\u00edna lipase(Tipo Ic). A hiperlipoproteinemia do tipo I geralmente se apresenta na inf\u00e2ncia com xantoma eruptivo e c\u00f3lica abdominal. As complica\u00e7\u00f5es incluem oclus\u00e3o da veia retiniana, pancreatite aguda, esteatose, organomegalia e lipemia retinal."},"en":{"language":"en","value":"Type I hyperlipoproteinemia exists in several forms: Lipoprotein lipase deficiency (Type Ia), due to a deficiency of lipoprotein lipase (LPL) or altered apolipoprotein C2, resulting in elevated chylomicrons, the particles that transfer fatty acids from the digestive tract to the liver. Familial apoprotein CII deficiency (Type Ib), a condition caused by a lack of lipoprotein lipase activator. Chylomicronemia due to circulating inhibitor of lipoprotein lipase (Type Ic). Type I hyperlipoproteinemia usually presents in childhood with eruptive xanthomata and abdominal colic. Complications include retinal vein occlusion, acute pancreatitis, steatosis and organomegaly, and lipaemia retinalis."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"8c19f130dbb710d0549439b47ec594f6261fa3db","datavalue":{"value":"https://id.who.int/icd/entity/2104488268","type":"string"},"datatype":"url"},"type":"statement","id":"Q98421$7E6CFA0F-0A26-4BAE-A218-DC7F70B50FBE","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"4a533550083af6ef4ed339177653c927020f9206","datavalue":{"value":"CID11:ID_2104488268","type":"string"},"datatype":"string"},"type":"statement","id":"Q98421$356D3BC0-60CA-4E8C-8969-2B365BE9A42E","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"f3a8a26b71ce17da83be2c4e30ba3f01f2613c40","datavalue":{"value":"dki-india-ID_2104488268","type":"string"},"datatype":"string"},"type":"statement","id":"Q98421$7B4464F0-8B3F-4BBE-B575-D9C34C37B87C","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q98421$BD0D746E-3AE7-4EF3-BA0E-90549A3FFF48","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q98421$BD5F255E-4DFD-4861-B1ED-DB484578A04C","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"378ac503ed43f21e1f461d2823a6ad59da580514","datavalue":{"value":{"time":"+2026-08-15T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q98421$9DEBE670-69CC-4F6C-B3A7-575863C8D425","rank":"normal"}]},"sitelinks":{}}}}