{"entities":{"Q97091":{"pageid":87484,"ns":120,"title":"Item:Q97091","lastrevid":548825,"modified":"2026-08-16T13:07:38Z","type":"item","id":"Q97091","labels":{"mul":{"language":"mul","value":"ID_8113015"},"pt-br":{"language":"pt-br","value":"C\u00e2ncer colorretal heredit\u00e1rio n\u00e3o poliposo"},"en":{"language":"en","value":"Hereditary nonpolyposis colorectal cancer"}},"descriptions":{"pt-br":{"language":"pt-br","value":"A s\u00edndrome de Lynch (HNPCC ou c\u00e2ncer colorretal heredit\u00e1rio n\u00e3o poliposo) \u00e9 uma condi\u00e7\u00e3o gen\u00e9tica autoss\u00f4mica dominante que tem um alto risco de c\u00e2ncer do c\u00f3lon, bem como outros c\u00e2nceres, incluindo est\u00f4mago, intestino delgado, f\u00edgado, ductos da ves\u00edcula biliar, trato urin\u00e1rio superior, c\u00e9rebro, pele e pr\u00f3stata. Mulheres com esse transtorno tamb\u00e9m t\u00eam um alto risco de c\u00e2ncer do endom\u00e9trio (revestimento do \u00fatero) e ov\u00e1rios. O risco aumentado para esses tipos de c\u00e2ncer se deve a muta\u00e7\u00f5es heredit\u00e1rias que comprometem o reparo de incompatibilidades do DNA."},"en":{"language":"en","value":"Lynch syndrome (HNPCC or Hereditary nonpolyposis colorectal cancer) is an autosomal dominant genetic condition which has a high risk of colon cancer as well as other cancers including stomach, small intestine, liver, gallbladder ducts, upper urinary tract, brain, skin, and prostate. Women with this disorder also have a high risk of cancer of the endometrium (lining of the uterus) and ovaries.The increased risk for these cancers is due to inherited mutations that impair DNA mismatch repair."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"91e237d5f6090e2928d7f393fc017fd46917d68d","datavalue":{"value":"https://id.who.int/icd/entity/8113015","type":"string"},"datatype":"url"},"type":"statement","id":"Q97091$7029377D-3843-4E6C-8DBB-30E15ECD14BF","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"277a88f01ca661ba103b9b58340e7ddbc9c4dcde","datavalue":{"value":"CID11:ID_8113015","type":"string"},"datatype":"string"},"type":"statement","id":"Q97091$D32AE2FF-5FF4-4493-AB55-F2AA67C2D05F","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"db36511b3288c10d38ae8cbba18838a69a952006","datavalue":{"value":"dki-india-ID_8113015","type":"string"},"datatype":"string"},"type":"statement","id":"Q97091$DDCACFD0-3143-4FB6-BD14-B5F76C27749C","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q97091$F527BB8B-74FC-43FD-A6C3-29E23221A3BB","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q97091$7B012A26-A9F1-4357-A7E5-D5679957C431","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"378ac503ed43f21e1f461d2823a6ad59da580514","datavalue":{"value":{"time":"+2026-08-15T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q97091$F1CE7696-E357-4D16-8264-CB462A111123","rank":"normal"}]},"sitelinks":{}}}}