{"entities":{"Q92046":{"pageid":82439,"ns":120,"title":"Item:Q92046","lastrevid":512327,"modified":"2026-08-16T07:12:06Z","type":"item","id":"Q92046","labels":{"mul":{"language":"mul","value":"ID_1906098371"},"pt-br":{"language":"pt-br","value":"Talassemia falciforme com crise com s\u00edndrome tor\u00e1cica aguda"},"en":{"language":"en","value":"Sickle cell thalassaemia with crisis with acute chest syndrome"}},"descriptions":{"pt-br":{"language":"pt-br","value":"Doen\u00e7a causada por uma muta\u00e7\u00e3o gen\u00e9tica da c\u00e9lula falciforme (HbS) de um progenitor e uma muta\u00e7\u00e3o da talassemia do outro progenitor. Esta doen\u00e7a \u00e9 caracterizada por hem\u00e1cias anormais r\u00edgidas em forma de foice e produ\u00e7\u00e3o anormal da cadeia beta em uma mol\u00e9cula de hemoglobina e s\u00edndrome tor\u00e1cica aguda. Esta doen\u00e7a pode apresentar palidez, icter\u00edcia, dor tor\u00e1cica aguda, sobrecarga de ferro, fadiga ou falta de ar. A confirma\u00e7\u00e3o \u00e9 feita por identifica\u00e7\u00e3o de muta\u00e7\u00f5es por meio de testes gen\u00e9ticos."},"en":{"language":"en","value":"A disease caused by genetically inherited sickle cell (HbS) mutation from one parent and a thalassemia mutation from the other parent. This disease is characterised by abnormal rigid sickle-shaped red blood cells and abnormal production of the beta chain in a haemoglobin molecule and, acute chest syndrome. This disease may present with pallor, jaundice, acute chest pain, iron overload, fatigue, or shortness of breath. Confirmation is by identification of mutations through genetic testing."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"11f677b282782321904b1ee69ab6497f1dd73104","datavalue":{"value":"https://id.who.int/icd/entity/1906098371","type":"string"},"datatype":"url"},"type":"statement","id":"Q92046$F70C139B-F491-441D-A4C2-D4E1344C4AD9","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"35c6b05390f281baf09b947e7fcdeca7c0ed77ad","datavalue":{"value":"CID11:ID_1906098371","type":"string"},"datatype":"string"},"type":"statement","id":"Q92046$08D8BC7F-4A71-4C2B-A23B-939CDDE0C841","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"cfd2dd9014d2f71e46693b7bbe9975524feeb7f1","datavalue":{"value":"dki-india-ID_1906098371","type":"string"},"datatype":"string"},"type":"statement","id":"Q92046$0B83AEDE-6144-4DA1-850C-9A7FFA8E2273","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q92046$25FEDA07-4A3A-436C-8325-85A9F2640343","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q92046$E830951F-871A-4333-9827-1610EEFFD670","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"378ac503ed43f21e1f461d2823a6ad59da580514","datavalue":{"value":{"time":"+2026-08-15T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q92046$244367A6-C656-4B0C-8016-B080C957820A","rank":"normal"}]},"sitelinks":{}}}}