{"entities":{"Q89191":{"pageid":79576,"ns":120,"title":"Item:Q89191","lastrevid":492078,"modified":"2026-08-15T15:45:44Z","type":"item","id":"Q89191","labels":{"mul":{"language":"mul","value":"ID_1209364172"},"pt-br":{"language":"pt-br","value":"Hemofilia B grave"},"en":{"language":"en","value":"Severe haemophilia B"}},"descriptions":{"pt-br":{"language":"pt-br","value":"Hemofilia B grave \u00e9 uma forma de hemofilia B (veja este termo) caracterizada por uma defici\u00eancia importante de fator IX, levando a hemorragias espont\u00e2neas frequentes e a sangramento anormal como resultado de ferimentos menores ou subsequente a cirurgias ou extra\u00e7\u00f5es dent\u00e1rias. Hemofilia B grave responde por cerca de 40% de todos os casos de hemofilia B. A atividade biol\u00f3gica do fator IX \u00e9 inferior a 1%. A transmiss\u00e3o \u00e9 recessiva ligada ao X, e o transtorno \u00e9 causado por muta\u00e7\u00f5es no gene F9 (Xq28), que codifica o fator IX da coagula\u00e7\u00e3o."},"en":{"language":"en","value":"Severe haemophilia B is a form of haemophilia B (see this term) characterised by a large deficiency of factor IX leading to frequent spontaneous haemorrhage and abnormal bleeding as a result of minor injuries, or following surgery or tooth extraction. Severe haemophilia B accounts for around 40% of all cases of haemophilia B. The biological activity of factor IX is below 1%. Transmission is X-linked recessive and the disorder is caused by mutations in the F9 gene (Xq28) encoding coagulation factor IX."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"f20ba3ee55740cacb3928aa4e788fa10bf4c204d","datavalue":{"value":"https://id.who.int/icd/entity/1209364172","type":"string"},"datatype":"url"},"type":"statement","id":"Q89191$E49ECEA4-0938-4E35-9144-234C59B8A3B8","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"8155819bf7fa39b7b1cad36979328c775717f598","datavalue":{"value":"CID11:ID_1209364172","type":"string"},"datatype":"string"},"type":"statement","id":"Q89191$74F289B7-6944-4850-9E7B-868C6AF7062F","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"e953a1b1cc92dc08e91d56f50e4369101e8425fd","datavalue":{"value":"dki-india-ID_1209364172","type":"string"},"datatype":"string"},"type":"statement","id":"Q89191$E84E9C2E-48A9-4D83-8606-552FA2EF78DC","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q89191$6A27618A-06F0-41C2-A32E-16C14B7D66B7","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q89191$A259D900-680D-4C1B-9FFC-E6F6BB239420","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q89191$9D70F5FC-4E87-4CF7-86F0-1C946C670465","rank":"normal"}]},"sitelinks":{}}}}