{"entities":{"Q88777":{"pageid":79162,"ns":120,"title":"Item:Q88777","lastrevid":489058,"modified":"2026-08-15T15:10:09Z","type":"item","id":"Q88777","labels":{"mul":{"language":"mul","value":"ID_643345953"},"pt-br":{"language":"pt-br","value":"Doen\u00e7a do enxerto versus hospedeiro cr\u00f4nica tardia"},"en":{"language":"en","value":"Late chronic graft-versus-host disease"}},"descriptions":{"pt-br":{"language":"pt-br","value":"Doen\u00e7a do enxerto-versus-hospedeiro (GVHD) cr\u00f4nica tardia usualmente se apresenta entre 150 e 300 dias ap\u00f3s o transplante. Pode se desenvolver a partir da forma liquenoide cr\u00f4nica precoce da GVHD ou pode surgir como manifesta\u00e7\u00e3o nova. \u00c9 caracterizada por l\u00edquen escleroso disseminado ou por espessamento da pele semelhante \u00e0 morfeia e poiquilodermia. Bolhas, eros\u00f5es, alopecia, cicatrizes conjuntivais e, eventualmente, fibroses profundas com contraturas articulares podem ocorrer. O quadro pode ser acompanhado de fibrose de outros \u00f3rg\u00e3os, incluindo pulm\u00e3o e f\u00edgado. GVHD cr\u00f4nica tardia pode causar morbidade significativa, desfigura\u00e7\u00e3o e incapacidade."},"en":{"language":"en","value":"Late chronic-graft-versus-host disease (GVHD) usually presents between 150 and 300 days after engraftment. It may develop from the early chronic lichenoid form of GVHD or may arise de novo. It is characterised by widespread lichen sclerosus or morphoea-like thickening of the skin and poikiloderma. Blisters, erosions, alopecia, conjunctival scarring and, eventually, deep fibrosis with joint contractures may occur. These may be accompanied by fibrosis of other organs including lung and liver. Late chronic GVHD can result in considerable morbidity, disfigurement and disability."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"e706d892ea247023d8fc150d238f111bb2c46c3c","datavalue":{"value":"https://id.who.int/icd/entity/643345953","type":"string"},"datatype":"url"},"type":"statement","id":"Q88777$E92EFA37-8BB7-4BC6-A7AD-C7EA83D0F95C","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"9a63d7098bbb1f0bf77b5a390b6050f51ef8174b","datavalue":{"value":"CID11:ID_643345953","type":"string"},"datatype":"string"},"type":"statement","id":"Q88777$5E5C9232-9694-4FC8-AF30-FF1ED8568AE0","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"8a0112e053831d23b082c752512d062f0aea1481","datavalue":{"value":"dki-india-ID_643345953","type":"string"},"datatype":"string"},"type":"statement","id":"Q88777$BA4D4BB2-FAA1-4D74-B35B-B4BE57574C1F","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q88777$5B78E6D4-ECA0-47D3-9589-F55CBEEA97FE","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q88777$A5C602A2-1E48-4F12-99E1-1F2489169BD9","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q88777$8D8C13C5-E549-4B3B-A32A-AD677B12AE8D","rank":"normal"}]},"sitelinks":{}}}}