{"entities":{"Q88649":{"pageid":79034,"ns":120,"title":"Item:Q88649","lastrevid":488112,"modified":"2026-08-15T14:58:36Z","type":"item","id":"Q88649","labels":{"mul":{"language":"mul","value":"ID_704273188"},"pt-br":{"language":"pt-br","value":"Miastenia gravis associada a timoma"},"en":{"language":"en","value":"Thymoma-associated myasthenia gravis"}},"descriptions":{"pt-br":{"language":"pt-br","value":"Em cerca de 15% dos pacientes com Miastenia Gravis positivos para receptor de acetilcolina (AChR), mais comum nas 4\u00aa a 6\u00aa d\u00e9cadas, a doen\u00e7a pode ser classificada como paraneopl\u00e1sica, geralmente associada a um timoma. O timoma nos pacientes com MG \u00e9 t\u00e3o ou menos maligno do que aquele sem MG. Anticorpos antiestriatais, incluindo antitina, anti-receptor de rianodina (RyR) e anticorpos Kv1.4, s\u00e3o encontrados com mais frequ\u00eancia em MG associada a timoma. Na MG quinase muscular espec\u00edfica (MuSK), o timoma \u00e9 raro, embora pequenos timomas tenham sido relatados."},"en":{"language":"en","value":"In about 15% of the Acetylcholine receptor (AChR) positive Myasthenia Gravis patients, most common in 4th to 6th decades, the disease can be classified as paraneoplastic, usually associated with a thymoma. Thymoma with MG is equally or less malignant than that without MG. Anti-striational antibodies including anti-titin, ryanodine receptor (RyR), and Kv1.4 antibodies are more frequently found in thymoma-associated MG. In Muscle-specific kinase (MuSK) MG thymoma is rare, albeit small thymomas have been reported."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"457d48070fb45bf4b7d27a564b49cb2b6fd8070d","datavalue":{"value":"https://id.who.int/icd/entity/704273188","type":"string"},"datatype":"url"},"type":"statement","id":"Q88649$89F1A5A5-5046-45BC-B49C-46EC61033F9F","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"1199736ff0f5b7df04aac9b5150fb301b2a7ade7","datavalue":{"value":"CID11:ID_704273188","type":"string"},"datatype":"string"},"type":"statement","id":"Q88649$3D9001F0-3250-4EE7-9F34-DA1509890633","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"70bd557f2d033deee3c187f446e83c486dd3e92b","datavalue":{"value":"dki-india-ID_704273188","type":"string"},"datatype":"string"},"type":"statement","id":"Q88649$12F45B14-AC24-452C-8B59-E2AA4E129C7C","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q88649$A18B78AF-D576-4B1B-8C76-A8A3C59742C9","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q88649$F8571972-E292-41A5-B930-E47638BE753F","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q88649$64F20C1D-BF94-496E-B548-35DBA9DB610B","rank":"normal"}]},"sitelinks":{}}}}