{"entities":{"Q85680":{"pageid":76065,"ns":120,"title":"Item:Q85680","lastrevid":466534,"modified":"2026-08-15T11:02:45Z","type":"item","id":"Q85680","labels":{"mul":{"language":"mul","value":"ID_1481454585"},"pt-br":{"language":"pt-br","value":"Ceratodermia palmoplantar n\u00e3o epidermol\u00edtica difusa"},"en":{"language":"en","value":"Diffuse non-epidermolytic palmoplantar keratoderma"}},"descriptions":{"pt-br":{"language":"pt-br","value":"A ceratodermia palmoplantar n\u00e3o epidermol\u00edtica difusa (MIM #600962) \u00e9 um transtorno autoss\u00f4mico dominante causado por muta\u00e7\u00f5es no gene da queratina 1. Apresenta-se na primeira inf\u00e2ncia com hiperqueratose amarela, uniforme e muito espessa em todo o p\u00e9 e se espalhando posteriormente para as palmas das m\u00e3os. H\u00e1 um corte acentuado no punho e nenhuma tend\u00eancia de se espalhar para as superf\u00edcies extensoras. Hiperidrose \u00e9 usual e infec\u00e7\u00e3o por dermat\u00f3fitos \u00e9 comum."},"en":{"language":"en","value":"Diffuse non-epidermolytic palmoplantar keratoderma (MIM #600962 ) is an autosomal dominant disorder caused by mutations in the keratin 1 gene. It presents in early childhood even, very thick, yellow hyperkeratosis over the whole of the foot and spreading later to the palms. There is a sharp cut-off at the wrist and no tendency to spread to extensor surfaces. Hyperhidrosis is usual and dermatophyte infection is common."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"ef1dd377bae882f1b3ae1b57d27327eb090acc63","datavalue":{"value":"https://id.who.int/icd/entity/1481454585","type":"string"},"datatype":"url"},"type":"statement","id":"Q85680$2FE100E0-6247-4EA1-8D59-0561737956E2","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"88553cbaf34048f8ba587e89d66fac232a2c7a38","datavalue":{"value":"CID11:ID_1481454585","type":"string"},"datatype":"string"},"type":"statement","id":"Q85680$97A6E0D8-B4B7-4EDF-81AB-A8C303021CD9","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"7309fd069b8532ec3b8006ec0401cb97f1b81529","datavalue":{"value":"dki-india-ID_1481454585","type":"string"},"datatype":"string"},"type":"statement","id":"Q85680$B58CE061-2942-4DE2-89A0-8B04CC9E79D1","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q85680$B22BFD4F-B84C-4818-A492-1C26E4A42B4C","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q85680$683FDEF5-FE9E-41AF-894F-2F6C4828473A","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q85680$5357E6E4-E723-4728-AAAA-D3432B0B8A24","rank":"normal"}]},"sitelinks":{}}}}