{"entities":{"Q85316":{"pageid":75701,"ns":120,"title":"Item:Q85316","lastrevid":463877,"modified":"2026-08-15T10:40:54Z","type":"item","id":"Q85316","labels":{"mul":{"language":"mul","value":"ID_1491982251"},"pt-br":{"language":"pt-br","value":"Hemofilia A moderadamente grave"},"en":{"language":"en","value":"Moderately severe haemophilia A"}},"descriptions":{"pt-br":{"language":"pt-br","value":"Hemofilia A moderadamente grave \u00e9 uma forma de hemofilia A (veja este termo), caracterizada pela defici\u00eancia de fator VIII, levando a sangramento anormal como resultado de ferimentos menores ou subsequente a cirurgias ou extra\u00e7\u00f5es dent\u00e1rias. Hemofilia A moderadamente grave responde por cerca de 20% de todos os casos de hemofilia A. A atividade biol\u00f3gica do fator VIII encontra-se entre 1% e 5%. Hemorragias espont\u00e2neas s\u00e3o raras. A transmiss\u00e3o \u00e9 recessiva ligada ao X, e o transtorno \u00e9 cuasado por muta\u00e7\u00f5es no gene F8 (Xq28), que codifica o fator VIII da coagula\u00e7\u00e3o."},"en":{"language":"en","value":"Moderately severe haemophilia A is a form of haemophilia A (see this term) characterised by factor VIII deficiency leading to abnormal bleeding as a result of minor injuries, or following surgery or tooth extraction. Moderately severe haemophilia A accounts for around 20% of all cases of haemophilia A. The biological activity of factor VIII is between 1% and 5%. Spontaneous haemorrhages are rare. Transmission is X-linked recessive and the disorder is caused by mutations in the F8 gene (Xq28) encoding coagulation factor VIII."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"fcab57bb7dd7676aff9a9cfcfc7ac393dd657131","datavalue":{"value":"https://id.who.int/icd/entity/1491982251","type":"string"},"datatype":"url"},"type":"statement","id":"Q85316$3EB8A385-AB63-4AB0-9A15-5C57AA4F1B98","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"1eb6ec0f2f12e0355ff9f5313cc569e1495c36a3","datavalue":{"value":"CID11:ID_1491982251","type":"string"},"datatype":"string"},"type":"statement","id":"Q85316$21A00ABC-0CED-469F-97DD-6A6892FD4E53","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"e1b3e6b0b1ce9db105f9df899de70f79118a3cac","datavalue":{"value":"dki-india-ID_1491982251","type":"string"},"datatype":"string"},"type":"statement","id":"Q85316$388A28CA-6426-4380-9AEE-031FDF259E5D","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q85316$F59FEDF8-43D5-4EA6-A912-B742B4D5A43C","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q85316$CC50482C-7CB1-48C1-861B-96D740A820AD","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q85316$CCAEF0D2-DBDB-431C-B363-470DCC07359C","rank":"normal"}]},"sitelinks":{}}}}