{"entities":{"Q84643":{"pageid":75028,"ns":120,"title":"Item:Q84643","lastrevid":458977,"modified":"2026-08-15T09:59:24Z","type":"item","id":"Q84643","labels":{"mul":{"language":"mul","value":"ID_585803264"},"pt-br":{"language":"pt-br","value":"Alguma miopatia miofibrilar especificada"},"en":{"language":"en","value":"Certain specified myofibrillar myopathy"}},"descriptions":{"pt-br":{"language":"pt-br","value":"A miopatia miofibrilar consiste em um padr\u00e3o patol\u00f3gico de dissolu\u00e7\u00e3o e degrada\u00e7\u00e3o miofibrilar levando, na maioria dos casos, ao ac\u00famulo de miotilina, desmina e alfaB-cristalina. A maioria dos pacientes desenvolve fraqueza na terceira \u00e0 quinta d\u00e9cada, embora haja relatos de in\u00edcio na inf\u00e2ncia e mais tarde na vida. Alguns se manifestam como uma miopatia grave de in\u00edcio progressivo no adulto com ou sem sinais de envolvimento card\u00edaco, mas em outros os sinais card\u00edacos podem ser a manifesta\u00e7\u00e3o principal ou exclusiva com cardiomiopatia, insufici\u00eancia card\u00edaca congestiva, bloqueio card\u00edaco e arritmias."},"en":{"language":"en","value":"Myofibrillary myopathy consists of a pathological pattern of myofibrillary dissolution and degradation leading in most cases to the accumulation of myotilin, desmin and \u03b1B-crystallin. Most patients develop weakness in the third to fifth decade, although there are reports of onset in infancy and later in life. Some manifest as a relentlessly progressive adult onset myopathy with or without signs of cardiac involvement, but in others the cardiac signs may the leading or exclusive manifestation with cardiomyopathy, congestive heart failure, heart block and arrhythmias."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"0ae696f0389a1ca6b20e6a27b62afea325bdf57e","datavalue":{"value":"https://id.who.int/icd/entity/585803264","type":"string"},"datatype":"url"},"type":"statement","id":"Q84643$A77A8B42-9CDB-4394-AF0B-1C19AD34231A","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"2a2f36a7550fc4266dc49ea60c5ab41014a25137","datavalue":{"value":"CID11:ID_585803264","type":"string"},"datatype":"string"},"type":"statement","id":"Q84643$4CCC5E65-891F-49D9-99C9-06BD26D65C8A","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"759f6653b835af2d6310eda537d22c0bd95fdd1e","datavalue":{"value":"dki-india-ID_585803264","type":"string"},"datatype":"string"},"type":"statement","id":"Q84643$5B923861-AD31-4EC2-8CFB-E4B6124C7EAB","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q84643$5080FD31-DC75-417F-859B-E2C5918179AE","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q84643$73043283-46A0-48BE-9EBD-4A904403FE33","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q84643$FD9B4BAB-DE12-47DC-AAE1-195227E9E916","rank":"normal"}]},"sitelinks":{}}}}