{"entities":{"Q84133":{"pageid":74518,"ns":120,"title":"Item:Q84133","lastrevid":455271,"modified":"2026-08-15T09:29:47Z","type":"item","id":"Q84133","labels":{"mul":{"language":"mul","value":"ID_290333867"},"pt-br":{"language":"pt-br","value":"Transtorno do espectro de neuromielite \u00f3ptica"},"en":{"language":"en","value":"Neuromyelitis optica spectrum disorder"}},"descriptions":{"pt-br":{"language":"pt-br","value":"Os transtornos do espectro da neuromielite \u00f3ptica (NMOSD) s\u00e3o dist\u00farbios desmielinizantes inflamat\u00f3rios do sistema nervoso central (SNC) que representam formas limitadas de neuromielite \u00f3ptica (NMO) [ver defini\u00e7\u00e3o de NMO] e n\u00e3o preenchem os crit\u00e9rios de diagn\u00f3stico de NMO de 2006, que requerem neurite \u00f3ptica e transversa mielite. NMOSDs requerem a detec\u00e7\u00e3o de aquaporina-4 IgG. Exemplos de NMOSDs incluem AQP4-IgG acompanhando neurite \u00f3ptica \u00fanica / recorrente ou mielite transversal \u00fanica / recorrente e tipicamente mielite longitudinalmente extensa (> 3 segmentos vertebrais). Os NMOSDs menos comuns incluem ataques de n\u00e1useas e v\u00f4mitos graves de les\u00f5es de \u00e1rea postrema e les\u00f5es cerebrais (por exemplo, encefalopatia revers\u00edvel posterior como s\u00edndrome ou encefalomielite disseminada aguda)._x000D_ _x000D_ Os autoanticorpos neurais associados incluem:_x000D_ _x000D_ AQP4-IgG (autoanticorpos aquaporina-4)"},"en":{"language":"en","value":"Neuromyelitis Optica Spectrum Disorders (NMOSD) are inflammatory demyelinating disorders of the central nervous system (CNS) which represent limited forms of Neuromyelitis Optica (NMO) [see NMO definition] and do not fulfill the 2006 NMO diagnostic criteria which requires both optic neuritis and transverse myelitis. NMOSD\u2019s require the detection of aquaporin-4 IgG. Examples of NMOSD\u2019s include AQP4-IgG accompanying either single/recurrent optic neuritis or single/recurrent typically longitudinally extensive (> 3 vertebral segments) transverse myelitis. Less common NMOSD\u2019s include attacks of severe nausea and vomiting from area postrema lesions and cerebral lesions (e.g. posterior reversible encephalopathy like syndrome or acute disseminated encephalomyelitis). Associated neural autoantibodies include: AQP4-IgG (aquaporin-4 autoantibodies)"}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"7623d31d5636a006f7329e6c85110402dcf1ed70","datavalue":{"value":"https://id.who.int/icd/entity/290333867","type":"string"},"datatype":"url"},"type":"statement","id":"Q84133$A0BD6399-12B9-405C-9EAB-214583D03865","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"11d8ede18136f107fc9538467b4b6b2c4fc20dc4","datavalue":{"value":"CID11:ID_290333867","type":"string"},"datatype":"string"},"type":"statement","id":"Q84133$53CA2E37-F89A-4DB2-B9B0-1FD347869AA3","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"14aad642978deb2c16b4271f47743ad565f4e5a7","datavalue":{"value":"dki-india-ID_290333867","type":"string"},"datatype":"string"},"type":"statement","id":"Q84133$93F763E4-355A-41B0-A393-A52D1A0F97BF","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q84133$E643090C-4FD6-4E89-B08C-C6F9A10AB6FC","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q84133$590B1173-AAB5-41D0-AAA7-B0ADC2607258","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q84133$4AE5EBE9-5419-4CE0-B1E8-C2E017AA6812","rank":"normal"}]},"sitelinks":{}}}}