{"entities":{"Q84128":{"pageid":74513,"ns":120,"title":"Item:Q84128","lastrevid":455233,"modified":"2026-08-15T09:29:30Z","type":"item","id":"Q84128","labels":{"mul":{"language":"mul","value":"ID_2061898171"},"pt-br":{"language":"pt-br","value":"Encefalite paraneopl\u00e1sica do tronco encef\u00e1lico"},"en":{"language":"en","value":"Paraneoplastic brainstem encephalitis"}},"descriptions":{"pt-br":{"language":"pt-br","value":"A encefalite paraneopl\u00e1sica do tronco encef\u00e1lico resulta de um ataque direcionado ao tronco encef\u00e1lico como consequ\u00eancia de uma resposta imune tumoral potencialmente eficaz iniciada por ant\u00edgenos onco-neurais derivados de um c\u00e2ncer sist\u00eamico, resultando em sinais e sintomas subagudos (geralmente neuropatias cranianas m\u00faltiplas, tamb\u00e9m hipoventila\u00e7\u00e3o) relacionados ao tronco cerebral. Outros sintomas podem incluir laringoespasmo, distonia da abertura da mand\u00edbula, opsoclonia-mioclonia e narcolepsia / cataplexia. O perfil de autoanticorpos no soro ou l\u00edquido cefalorraquidiano prediz o tipo de c\u00e2ncer [ver encefalite paraneopl\u00e1sica do tronco cerebral: defini\u00e7\u00e3o positiva de autoanticorpo neural]. A resson\u00e2ncia magn\u00e9tica pode ser normal ou revelar anormalidades do tronco cerebral e o l\u00edquido espinhal geralmente \u00e9 inflamat\u00f3rio. Outras causas de encefalite do tronco cerebral (por exemplo, infec\u00e7\u00f5es) devem ser exclu\u00eddas."},"en":{"language":"en","value":"Paraneoplastic brainstem encephalitis results from a targeted attack on the brainstem as a consequence of a potentially effective tumour immune response initiated by onco-neural antigens derived from a systemic cancer resulting in subacute symptoms and signs (usually multiple cranial neuropathies, also hypoventilation) referable to the brainstem. Other symptoms may include laryngospasm, jaw opening dystonia, opsoclonus-myoclonus and narcolepsy/cataplexy. The autoantibody profile in the serum or cerebrospinal fluid predicts the cancer type [see paraneoplastic brainstem encephalitis: neural autoantibody positive definition]. MRI may be normal or reveal brainstem abnormalities and spinal fluid is usually inflammatory. Other causes of brainstem encephalitis (e.g. infections) should be excluded."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"3472fb67d4048345213d597ef463d4859f1e88f3","datavalue":{"value":"https://id.who.int/icd/entity/2061898171","type":"string"},"datatype":"url"},"type":"statement","id":"Q84128$4C776C6F-6DB3-453C-A9A8-08BCEC840846","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"561eaf572c8d8d524f16173d5786fefd95a91932","datavalue":{"value":"CID11:ID_2061898171","type":"string"},"datatype":"string"},"type":"statement","id":"Q84128$6EC50221-FF79-48B6-8ABC-172FD9FF632E","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"fa0e8a3f7de70f86325508d044cdc1505a97b557","datavalue":{"value":"dki-india-ID_2061898171","type":"string"},"datatype":"string"},"type":"statement","id":"Q84128$A6B9E67F-62FC-4471-8710-AF6BCA0B2302","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q84128$DF54262A-2090-4210-9C16-4000AACB86A9","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q84128$F818ED7F-7D62-4E39-8279-A73E869305EB","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q84128$06D7A3B6-CD3E-45FD-ADBB-6F08F80BE4E7","rank":"normal"}]},"sitelinks":{}}}}