{"entities":{"Q84065":{"pageid":74450,"ns":120,"title":"Item:Q84065","lastrevid":454784,"modified":"2026-08-15T09:25:53Z","type":"item","id":"Q84065","labels":{"mul":{"language":"mul","value":"ID_1308322963"},"pt-br":{"language":"pt-br","value":"Miopatia necrosante paraneopl\u00e1sica"},"en":{"language":"en","value":"Paraneoplastic necrotising myopathy"}},"descriptions":{"pt-br":{"language":"pt-br","value":"A miopatia necrosante paraneopl\u00e1sica \u00e9 uma miopatia aguda ou subaguda com fraqueza proximal e mialgia facultativa e dor muscular. A CK pode estar acentuadamente elevada. O in\u00edcio e o padr\u00e3o cl\u00ednico assemelham-se a Dermatomiosite (DM) e Poliomiosite (PM), tornando-se rapidamente incapacitante em 2-3 meses._x000D_ A histologia mostra necrose muscular dispersa, macr\u00f3fagos e escassos infiltrados focais de c\u00e9lulas T. A deposi\u00e7\u00e3o do complemento C5b-9 pode aparecer nas fibras musculares._x000D_ Ocorre em v\u00e1rios tipos de c\u00e2ncer, em particular nos c\u00e2nceres de pulm\u00e3o, mama e gastrointestinal."},"en":{"language":"en","value":"Paraneoplastic necrotising myopathy is an acute or subacute myopathy with proximal weakness, and facultative myalgia and muscle pain. CK can be markedly elevated. The onset and clinical pattern resembles DM and PM, it is rapidly disabling within 2-3 months. Histology shows scattered muscle necrosis, macrophages and scarce focal T cell infiltrates. C5b-9 complement deposition can appear in muscle fibres. It occurs in several cancer types in particular lung, breast and gastrointestinal cancers."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"6b865ea2103ab03606c0c4b3f46b6ad32a9aee85","datavalue":{"value":"https://id.who.int/icd/entity/1308322963","type":"string"},"datatype":"url"},"type":"statement","id":"Q84065$F290F9E2-80A7-4449-BE86-2385444E7B61","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"4a7b44cb9734e59149adcfe34b9646b42b34fe61","datavalue":{"value":"CID11:ID_1308322963","type":"string"},"datatype":"string"},"type":"statement","id":"Q84065$2C75D4C2-1DC9-4EE9-8421-B6077A272DE4","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"cf787bbc48008f1aecd8fcc14795bc428bf101ad","datavalue":{"value":"dki-india-ID_1308322963","type":"string"},"datatype":"string"},"type":"statement","id":"Q84065$EAD2781B-E691-46EF-BC4F-EE62789A53ED","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q84065$BA015BC2-9F8D-4387-9B7C-A9283E8A0253","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q84065$BCB7ACFC-FFCC-4824-901F-C02652D51777","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q84065$4DAD4493-18EC-4978-A910-6DFF7B0B7ED7","rank":"normal"}]},"sitelinks":{}}}}