{"entities":{"Q67672":{"pageid":58050,"ns":120,"title":"Item:Q67672","lastrevid":336535,"modified":"2026-08-14T15:30:28Z","type":"item","id":"Q67672","labels":{"mul":{"language":"mul","value":"ID_1395439137"},"pt-br":{"language":"pt-br","value":"Doen\u00e7a de Erdheim-Chester"},"en":{"language":"en","value":"Erdheim-Chester disease"}},"descriptions":{"pt-br":{"language":"pt-br","value":"A doen\u00e7a de Erdheim-Chester \u00e9 uma histiocitose Classe IIa (c\u00e9lulas n\u00e3o Langerhans) de etiologia desconhecida, caracterizada por uma infiltra\u00e7\u00e3o xantogranulomatosa de v\u00edsceras, ossos, retroperit\u00f4nio e pele por histi\u00f3citos carregados de lip\u00eddios e fibrose circundante. Apresenta-se mais comumente na vida adulta, com dor nos ossos, tipicamente ao redor dos joelhos e tornozelos. Exoftalmia, diabetes insipidus, xantoma cut\u00e2neo, fibrose pulmonar e uma ampla gama de complica\u00e7\u00f5es decorrentes da infiltra\u00e7\u00e3o retroperitoneal e do SNC s\u00e3o todos bem reconhecidos."},"en":{"language":"en","value":"Erdheim-Chester disease is a Class IIa (non-Langerhans cell) histiocytosis of unknown aetiology characterised by a xanthogranulomatous infiltration of viscera, bones, retroperitoneum and skin by lipid-laden histiocytes and surrounding fibrosis. It most commonly presents in adult life with bone pain, typically around the knees and ankles. Exophthalmos, diabetes insipidus, cutaneous xanthomata, pulmonary fibrosis and a broad range of complications resulting from retroperitoneal and CNS infiltration are all well recognised."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"c462d93e3cf73411503c5966dc4b4876adc32803","datavalue":{"value":"https://id.who.int/icd/entity/1395439137","type":"string"},"datatype":"url"},"type":"statement","id":"Q67672$3C629400-C394-4383-B5BE-135C47A64653","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"de5ee1a6e69bc2d57d878caa3df485dd4e8b66fd","datavalue":{"value":"CID11:ID_1395439137","type":"string"},"datatype":"string"},"type":"statement","id":"Q67672$EE8FE0C3-547F-4046-AC5F-5F20725D695F","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"1841d6c927e039ed1e3a30334a543d788bce90c9","datavalue":{"value":"dki-india-ID_1395439137","type":"string"},"datatype":"string"},"type":"statement","id":"Q67672$D7295A10-63A1-4A57-9465-CF59DF751BFB","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q67672$F344506B-97B9-437A-931A-D036D1D7A1CA","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q67672$2C67A15D-3970-4B97-A054-EA332664122A","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q67672$0731E1D3-2311-4311-AC81-F048CAFCDC34","rank":"normal"}]},"sitelinks":{}}}}