{"entities":{"Q62720":{"pageid":53093,"ns":120,"title":"Item:Q62720","lastrevid":301284,"modified":"2026-08-14T10:12:13Z","type":"item","id":"Q62720","labels":{"mul":{"language":"mul","value":"ID_1183730789"},"pt-br":{"language":"pt-br","value":"Ictiose epidermol\u00edtica"},"en":{"language":"en","value":"Epidermolytic ichthyosis"}},"descriptions":{"pt-br":{"language":"pt-br","value":"Ictiose epidermol\u00edtica \u00e9 um transtorno gen\u00e9tico da pele causado por muta\u00e7\u00f5es no gene da queratina 10 (KRT10). A heran\u00e7a geralmente \u00e9 autoss\u00f4mica dominante, mas at\u00e9 50% dos casos s\u00e3o espor\u00e1dicos. Pode se manifestar ao nascimento com eritrodermia e grave forma\u00e7\u00e3o de bolhas, mas com a idade as bolhas tendem a ser menos graves e o eritema menos proeminente. Hiperceratose progressiva se desenvolve, acentuada nas flexuras articulares. A expectativa de vida \u00e9 geralmente normal, embora a doen\u00e7a possa ser gravemente incapacitante."},"en":{"language":"en","value":"Epidermolytic ichthyosis is a genetic skin disorder due to mutations in the keratin 10 gene (KRT10). Inheritance is usually autosomal dominant but up to 50% of cases are sporadic. It may manifest at birth with erythroderma and severe blistering but with age blistering tends to be less severe and erythema less prominent. Progressive hyperkeratosis develops, accentuated at joint flexures. Life expectancy is usually normal although the disease can be severely incapacitating."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"92489e5f89da6c2ccf1398418571554414b524e1","datavalue":{"value":"https://id.who.int/icd/entity/1183730789","type":"string"},"datatype":"url"},"type":"statement","id":"Q62720$08424B96-2507-4FE0-8924-9B61CF59583A","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"566a897e43643456546406e84a7f9b992cdda157","datavalue":{"value":"CID11:ID_1183730789","type":"string"},"datatype":"string"},"type":"statement","id":"Q62720$997F3C23-075D-4C04-8128-35E5300E283F","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"8b74b81ef4ba638a46d321138b09a53f74c5a3f1","datavalue":{"value":"dki-india-ID_1183730789","type":"string"},"datatype":"string"},"type":"statement","id":"Q62720$B8BB6101-652E-41E3-952F-67B990EF04E6","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q62720$997BD434-88E2-4DF6-9E4A-A7C08B798A7B","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q62720$B66890BE-60B4-480C-B874-9B0F692861F5","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q62720$9147D24C-5296-453F-9906-57A8D6CB2F61","rank":"normal"}]},"sitelinks":{}}}}