{"entities":{"Q58857":{"pageid":49230,"ns":120,"title":"Item:Q58857","lastrevid":273783,"modified":"2026-08-14T06:25:11Z","type":"item","id":"Q58857","labels":{"mul":{"language":"mul","value":"ID_1785140754"},"pt-br":{"language":"pt-br","value":"Xantoma disseminado"},"en":{"language":"en","value":"Xanthoma disseminatum"}},"descriptions":{"pt-br":{"language":"pt-br","value":"Xantoma disseminado \u00e9 uma doen\u00e7a n\u00e3o familiar rara, caracterizada por prolifera\u00e7\u00e3o de c\u00e9lulas histioc\u00edticas em que a deposi\u00e7\u00e3o lip\u00eddica \u00e9 um evento secund\u00e1rio. A doen\u00e7a afeta predominantemente crian\u00e7as e adultos jovens do sexo masculino, com envolvimento de pele, mucosas oculares e do trato respirat\u00f3rio superior, meninges e raramente outros \u00f3rg\u00e3os, incluindo f\u00edgado, ba\u00e7o e medula \u00f3ssea. As les\u00f5es cut\u00e2neas do xantoma disseminado s\u00e3o p\u00e1pulas e n\u00f3dulos eritematosos, amarelo-acastanhados que est\u00e3o distribu\u00eddos simetricamente em tronco, face e extremidades proximais. As les\u00f5es podem tornar-se confluentes, principalmente nas flexuras, formando placas xantomatosas. A doen\u00e7a pode persistir por muitos anos."},"en":{"language":"en","value":"Xanthoma disseminatum is a rare non-familial disease, characterised by proliferation of histiocytic cells in which lipid deposition is a secondary event. The disease predominantly affects male children and young adults, with involvement of the skin, mucous membranes of eyes and upper respiratory tract, the meninges and rarely other organs including liver, spleen and bone marrow. The skin lesions of xanthoma disseminatum are erythematous, yellow-brown papules and nodules, which are symmetrically distributed on the trunk, face and proximal extremities. The lesions may become confluent, especially in flexures, to form xanthomatous plaques. The disease may persist for many years."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"702f2aac1466989603cdde43eb95905b5f4111f1","datavalue":{"value":"https://id.who.int/icd/entity/1785140754","type":"string"},"datatype":"url"},"type":"statement","id":"Q58857$4413A4F7-2214-4EC5-8546-E500A16784F0","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"5ae2fb55a733a9a06c402c3b781700317add19f6","datavalue":{"value":"CID11:ID_1785140754","type":"string"},"datatype":"string"},"type":"statement","id":"Q58857$7C79CFA8-EE80-4531-9D92-FC01CD76EC95","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"c82fd3f3fdc1fccf47fa8ed0976e76abc26b5e91","datavalue":{"value":"dki-india-ID_1785140754","type":"string"},"datatype":"string"},"type":"statement","id":"Q58857$A17B69B6-0868-4436-BED8-2BD1BF239D7A","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q58857$856846E7-17FA-491B-AE98-F02D689826DD","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q58857$FE53288C-150B-4E2F-BEE2-B6AE53A1B498","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q58857$BB7B4BD4-3835-42B6-80E6-4669A834129F","rank":"normal"}]},"sitelinks":{}}}}