{"entities":{"Q46418":{"pageid":36789,"ns":120,"title":"Item:Q46418","lastrevid":181007,"modified":"2026-08-13T14:59:10Z","type":"item","id":"Q46418","labels":{"mul":{"language":"mul","value":"GB81"},"pt-br":{"language":"pt-br","value":"Doen\u00e7a renal polic\u00edstica autoss\u00f4mica dominante"},"en":{"language":"en","value":"Autosomal dominant polycystic kidney disease"}},"descriptions":{"pt-br":{"language":"pt-br","value":"Cistos m\u00faltiplos em ambos os rins aumentando em n\u00famero e tamanho a partir da adolesc\u00eancia, associados ao desenvolvimento de hipertens\u00e3o e insufici\u00eancia renal cr\u00f4nica. O padr\u00e3o familiar autoss\u00f4mico dominante \u00e9 comum e devido a muta\u00e7\u00f5es nos cromossomos 16 e 4. As manifesta\u00e7\u00f5es n\u00e3o renais podem incluir cistos no f\u00edgado e menos comumente no p\u00e2ncreas. Aneurismas arteriais cerebrais com hemorragia subaracnoide e outras anormalidades vasculares n\u00e3o renais tamb\u00e9m podem ocorrer."},"en":{"language":"en","value":"Multiple cysts in both kidneys increasing in number and size from adolescence, associated with development of hypertension and chronic renal failure. Autosomal dominant familial pattern is usual and due to mutations on chromosomes 16 and 4. Non-renal manifestations can include cysts in the liver and less commonly pancreas. Cerebral arterial aneurysms with subarachnoid haemorrhage, and other non-renal vascular abnormalities can also occur."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"e0304c42b52a5eea9521d0ad44e860bbf4113a44","datavalue":{"value":"https://id.who.int/icd/entity/91220434","type":"string"},"datatype":"url"},"type":"statement","id":"Q46418$0B244230-9A38-42F3-96A6-8ACA42F03FA7","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"047608b1a3b82bdf3163b29bdfa4945a995d53e2","datavalue":{"value":"CID11:GB81","type":"string"},"datatype":"string"},"type":"statement","id":"Q46418$58341D07-4396-4CFE-B588-ACF1C502CF8E","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"97f35fb1fdb29bde0e49eb1619d9757a21eb383f","datavalue":{"value":"dki-india-GB81","type":"string"},"datatype":"string"},"type":"statement","id":"Q46418$527E4CAE-63D3-45BE-BAC1-16000118D05E","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q46418$2CF15D8C-6E1A-4119-AD3F-3DDA05597BDD","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q46418$5CC08F98-7EA3-4C71-9F46-886990BF8E94","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q46418$C5853AB0-88E5-4C15-ACB6-6966AAA7F63A","rank":"normal"}],"P89":[{"mainsnak":{"snaktype":"value","property":"P89","hash":"9c4fadaf34dc5620ee19d750722f46b98cc7e2e3","datavalue":{"value":{"entity-type":"item","numeric-id":612,"id":"Q612"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q46418$0DB5D551-C81C-41B3-B4A9-926337380023","rank":"normal"}]},"sitelinks":{}}}}