{"entities":{"Q46328":{"pageid":36699,"ns":120,"title":"Item:Q46328","lastrevid":180166,"modified":"2026-08-13T14:50:12Z","type":"item","id":"Q46328","labels":{"mul":{"language":"mul","value":"LB16.1"},"pt-br":{"language":"pt-br","value":"Doen\u00e7a de Hirschsprung"},"en":{"language":"en","value":"Hirschsprung disease"}},"descriptions":{"pt-br":{"language":"pt-br","value":"Esta \u00e9 uma anomalia do desenvolvimento que afeta o trato intestinal, caracterizada pela aus\u00eancia cong\u00eanita de c\u00e9lulas ganglionares mioent\u00e9ricas (aganglionose) em um segmento do intestino grosso. Devido \u00e0 aus\u00eancia de inerva\u00e7\u00e3o intr\u00ednseca das camadas musculares do segmento afetado, ocorre perda da fun\u00e7\u00e3o motora. Isso resulta em um c\u00f3lon anormalmente grande ou dilatado (megac\u00f3lon cong\u00eanito) com oclus\u00e3o intestinal ou constipa\u00e7\u00e3o. Essa condi\u00e7\u00e3o se torna evidente logo ap\u00f3s o nascimento."},"en":{"language":"en","value":"This is a developmental anomaly affecting the intestinal tract characterised by congenital absence of myenteric ganglion cells (aganglionosis) in a segment of the large bowel. Due to the absence of intrinsic innervation of the muscle layers of the affected segment, there is a loss of motor function. This results in an abnormally large or dilated colon (congenital megacolon) with intestinal occlusion or constipation. This condition becomes evident shortly after birth."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"428d0f12a8d516b157432d635f9df8b0af464011","datavalue":{"value":"https://id.who.int/icd/entity/1772690306","type":"string"},"datatype":"url"},"type":"statement","id":"Q46328$96CA8983-BF90-4E22-BBF2-2E929E20645B","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"6a75cd6bcf150cbf70dbf695bc796e324dc75ef8","datavalue":{"value":"CID11:LB16.1","type":"string"},"datatype":"string"},"type":"statement","id":"Q46328$F4AB36BC-3D29-46B2-ABF9-0D054CA0A4F0","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"d2c6ffca3a3d3e6e2b2531e51fb8f3ca6693c25c","datavalue":{"value":"dki-india-LB16.1","type":"string"},"datatype":"string"},"type":"statement","id":"Q46328$5D01207D-5EA8-47A1-B127-2CBAD61E5B54","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q46328$D960F2BE-0904-4511-A366-DFA3F7804993","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q46328$B7D7864D-1D65-4003-8383-650B20A087EA","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q46328$079B5924-E592-4C1A-BC2D-3F3F4971E873","rank":"normal"}],"P89":[{"mainsnak":{"snaktype":"value","property":"P89","hash":"5d591655c68f2871ba48ed63f499d9547e5de555","datavalue":{"value":{"entity-type":"item","numeric-id":431,"id":"Q431"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q46328$B8685259-B2DF-4700-9D4A-506AD492811A","rank":"normal"}]},"sitelinks":{}}}}