{"entities":{"Q44713":{"pageid":35081,"ns":120,"title":"Item:Q44713","lastrevid":166036,"modified":"2026-08-13T12:19:04Z","type":"item","id":"Q44713","labels":{"mul":{"language":"mul","value":"GB90.43"},"pt-br":{"language":"pt-br","value":"S\u00edndrome de Bartter"},"en":{"language":"en","value":"Bartter syndrome"}},"descriptions":{"pt-br":{"language":"pt-br","value":"A s\u00edndrome de Bartter \u00e9 uma doen\u00e7a tubular renal gen\u00e9tica caracterizada pela associa\u00e7\u00e3o de alcalose hipocal\u00eamica, aumento dos n\u00edveis plasm\u00e1ticos de renina e aldosterona, redu\u00e7\u00e3o da press\u00e3o arterial e resist\u00eancia vascular \u00e0 angiotensina II. Duas formas da doen\u00e7a podem ser distinguidas de acordo com crit\u00e9rios cl\u00ednicos: uma s\u00edndrome de Bartter pr\u00e9-natal ou infantil (a maioria dos pacientes com gen\u00f3tipos I, II e IV), caracterizada por polidr\u00e2mnio, parto prematuro, poli\u00faria, desidrata\u00e7\u00e3o, hipercalci\u00faria e nefrocalcinose; e a s\u00edndrome de Bartter cl\u00e1ssica (a maioria pacientes com gen\u00f3tipo III, mas tamb\u00e9m alguns pacientes do tipo IV), manifestando-se como poli\u00faria-polidipsia desde a primeira inf\u00e2ncia-inf\u00e2ncia at\u00e9 a idade adulta, desidrata\u00e7\u00e3o e um atraso vari\u00e1vel na curva de crescimento altura-peso."},"en":{"language":"en","value":"Bartter syndrome is a genetic renal tubular disease characterised by the association of hypokalaemic alkalosis, increased levels of plasma renin and aldosterone, low blood pressure and vascular resistance to angiotensin II. Two forms of the disease can be distinguished according to clinical criteria: an antenatal or infantile Bartter syndrome (most patients with genotypes I, II and IV), characterised by polyhydramnios, premature delivery, polyuria, dehydration, hypercalciuria and nephrocalcinosis; and classical Bartter syndrome (mostly patients with genotype III, but also some type IV patients), manifesting as polyuria-polydipsia in infancy-childhood through to adulthood, dehydration and a variable delay in the height-weight growth curve."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"09b184a9aac9187ab6603137c9f5a6a69031cd26","datavalue":{"value":"https://id.who.int/icd/entity/777233947","type":"string"},"datatype":"url"},"type":"statement","id":"Q44713$660264B7-8BC4-4B3D-9705-267D222ADF96","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"7905656a63a1bb8d95755f85f73dc37a48656356","datavalue":{"value":"CID11:GB90.43","type":"string"},"datatype":"string"},"type":"statement","id":"Q44713$8FABA8DC-EC7B-42E5-8B00-7826FCF9812E","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"2f7da80b0ef03112797539a93cc14c30900eae93","datavalue":{"value":"dki-india-GB90.43","type":"string"},"datatype":"string"},"type":"statement","id":"Q44713$7761F613-7AAF-4FD9-9013-9E1FD87F7B2E","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q44713$261F7EF5-B033-4067-90B2-39C08ED54656","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q44713$0DD1C8F8-CCAE-4ADF-8438-406D7F054188","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q44713$9BE92477-97BF-429B-8942-CA76D1A420FE","rank":"normal"}],"P89":[{"mainsnak":{"snaktype":"value","property":"P89","hash":"acf63eb5c31a2f19cc379f3a6381d3f0e5c7dd1f","datavalue":{"value":{"entity-type":"item","numeric-id":20495,"id":"Q20495"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q44713$99C0B0E5-C321-4C29-8FDB-54FE4FE524D3","rank":"normal"}]},"sitelinks":{}}}}