{"entities":{"Q44666":{"pageid":35034,"ns":120,"title":"Item:Q44666","lastrevid":165617,"modified":"2026-08-13T12:14:22Z","type":"item","id":"Q44666","labels":{"mul":{"language":"mul","value":"GB50"},"pt-br":{"language":"pt-br","value":"Nefrite t\u00fabulo-intersticial aguda"},"en":{"language":"en","value":"Acute tubulo-interstitial nephritis"}},"descriptions":{"pt-br":{"language":"pt-br","value":"Doen\u00e7a caracterizada por inflama\u00e7\u00e3o aguda dos, e dano aos, t\u00fabulos e interst\u00edcio renal, geralmente acompanhada por insufici\u00eancia renal aguda (les\u00e3o renal aguda). A histologia mostra infiltrado inflamat\u00f3rio agudo no interst\u00edcio com edema e necrose de c\u00e9lulas tubulares, e frequentemente eosin\u00f3filos e plasm\u00f3citos proeminentes. Geralmente devida a uma rea\u00e7\u00e3o al\u00e9rgica ou imunol\u00f3gica a um al\u00e9rgeno identific\u00e1vel. Geralmente acompanhada por insufici\u00eancia renal aguda, que pode ser revers\u00edvel se o al\u00e9rgeno for retirado rapidamente com ou sem administra\u00e7\u00e3o de corticosteroides. Pode causar nefrite tubulointersticial cr\u00f4nica, particularmente se a exposi\u00e7\u00e3o ao al\u00e9rgeno n\u00e3o for de curto prazo. Pode estar associada a outros sinais de uma rea\u00e7\u00e3o al\u00e9rgica, como erup\u00e7\u00e3o cut\u00e2nea ou febre."},"en":{"language":"en","value":"A disease characterised by acute inflammation of, and damage to, tubules and the interstitium of the kidney, usually accompanied by acute renal failure (acute kidney injury). Histology shows acute inflammatory infiltrate in the interstitium with oedema and tubular cell necrosis, and often prominent eosinophils and plasma cells. Usually due to an allergic or immunological reaction to an identifiable allergen. Usually accompanied by acute renal failure which may be reversible if the allergen is withdrawn expeditiously with or without corticosteroid administration. Can lead to chronic tubulointerstitial nephritis, particularly if the allergen exposure is not short term. May be associated with other signs of an allergic reaction such as rash or fever."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"1f711bbb68dc2962597219e8f59d916ed8e53ee5","datavalue":{"value":"https://id.who.int/icd/entity/370349933","type":"string"},"datatype":"url"},"type":"statement","id":"Q44666$01D521D0-1DB3-4FEA-AC07-1A1A9D33F52C","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"cf6438e546a94d6b8c65e45e54a414a79a80f40a","datavalue":{"value":"CID11:GB50","type":"string"},"datatype":"string"},"type":"statement","id":"Q44666$19217E52-0D02-493E-AC1C-F416E5D8AA57","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"437df8d34b396545a43d0a554693187089a0daab","datavalue":{"value":"dki-india-GB50","type":"string"},"datatype":"string"},"type":"statement","id":"Q44666$F68741D2-2FE2-4959-8DA5-74E9B4594E8E","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q44666$4E2DA1A5-8D5E-44AE-9B74-BD2AB4E9B4D4","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q44666$89DDB17F-4501-4F1E-9EC9-B31BD10EE2F5","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q44666$9A7DB9FE-6781-4FCA-BC93-ADE8D9EFEB9E","rank":"normal"}],"P89":[{"mainsnak":{"snaktype":"value","property":"P89","hash":"186cf353dab9bc77615f437e1e4f9594a18114b9","datavalue":{"value":{"entity-type":"item","numeric-id":20429,"id":"Q20429"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q44666$32CE2266-7EAC-4AE9-8B6C-D16F92060A5D","rank":"normal"}]},"sitelinks":{}}}}