{"entities":{"Q44383":{"pageid":34751,"ns":120,"title":"Item:Q44383","lastrevid":163170,"modified":"2026-08-13T11:49:41Z","type":"item","id":"Q44383","labels":{"mul":{"language":"mul","value":"4A41.11"},"pt-br":{"language":"pt-br","value":"Polimiosite paraneopl\u00e1sica"},"en":{"language":"en","value":"Paraneoplastic polymyositis"}},"descriptions":{"pt-br":{"language":"pt-br","value":"Paraneoplasia \u00e9 uma entidade rara associada ao c\u00e2ncer. Apresenta-se de forma subaguda ou aguda como fraqueza proximal, muitas vezes incluindo os flexores do pesco\u00e7o, disfagia, raramente envolvendo os m\u00fasculos respirat\u00f3rios e o cora\u00e7\u00e3o. \u00c0s vezes, ocorre dor muscular ou mialgia. A histopatologia muscular mostra uma toxicidade linfocit\u00e1ria mediada por c\u00e9lulas contra as fibras musculares em \u00e1reas focais de inflama\u00e7\u00e3o no tecido conjuntivo perimisial e nos vasos sangu\u00edneos circundantes. As fibras musculares podem ser destru\u00eddas por c\u00e9lulas T citot\u00f3xicas._x000D_ Linfoma n\u00e3o-Hodgkin, carcinoma de pulm\u00e3o e bexiga s\u00e3o os tipos de c\u00e2ncer associados mais frequentemente observados."},"en":{"language":"en","value":"Paraneoplastic is a rare cancer associated entity. It presents sub-, or acutely with proximal weakness, often including the neck flexors, dysphagia, rarely the respiratory muscles and the heart are involved. Sometimes muscle pain or myalgia occur. Myopathology shows a targeted, cell-mediated lymphocyte toxicity against muscle fibres in focal areas of inflammation within perimysial connective tissue and surrounding blood vessels. Muscle fibres may be destroyed by cytotoxic T cells. Non-Hodgkin\u2019s lymphoma, lung, and bladder carcinoma are the most frequently observed associated cancer types."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"99e171215931a0be75d0b80846b5c9c0c4969875","datavalue":{"value":"https://id.who.int/icd/entity/113898480","type":"string"},"datatype":"url"},"type":"statement","id":"Q44383$D517FE1E-90E5-4731-9792-5725927F8C26","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"fa02846e08909ea9e051516f0b160c6af597155a","datavalue":{"value":"CID11:4A41.11","type":"string"},"datatype":"string"},"type":"statement","id":"Q44383$25BF7933-4110-4E96-9806-1FEE4D35F5D0","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"7aab387401d432059e9a96cf16e1d4c0810707ee","datavalue":{"value":"dki-india-4A41.11","type":"string"},"datatype":"string"},"type":"statement","id":"Q44383$B82038F1-2725-4198-BDA9-345EAF8E513F","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q44383$16D828A5-8EA5-4F66-AC82-7E389726F463","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q44383$7E229864-D86C-47F6-9BB7-5A3BC833DB0D","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q44383$50E64CBF-D3D1-405D-92D5-78E80AAE4932","rank":"normal"}],"P89":[{"mainsnak":{"snaktype":"value","property":"P89","hash":"89d64dbc88ee44ce61068f6463b51ab864347706","datavalue":{"value":{"entity-type":"item","numeric-id":19932,"id":"Q19932"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q44383$155C15D1-3E0B-4CCA-83B2-E915DE2CB9AC","rank":"normal"}]},"sitelinks":{}}}}