{"entities":{"Q43853":{"pageid":34221,"ns":120,"title":"Item:Q43853","lastrevid":158440,"modified":"2026-08-13T11:02:26Z","type":"item","id":"Q43853","labels":{"mul":{"language":"mul","value":"EH63.0"},"pt-br":{"language":"pt-br","value":"S\u00edndrome de Stevens-Johnson induzida por droga"},"en":{"language":"en","value":"Drug-induced Stevens-Johnson syndrome"}},"descriptions":{"pt-br":{"language":"pt-br","value":"Uma das quatro formas principais de rea\u00e7\u00f5es cut\u00e2neas graves adversas \u00e0 droga (RCGAD), sendo caracterizada por inflama\u00e7\u00e3o, rea\u00e7\u00e3o bolhosa e eros\u00f5es de pele e mucosas. Por defini\u00e7\u00e3o, h\u00e1 o envolvimento de pelo menos uma mucosa e o descolamento da pele limita-se a menos de 10% da \u00e1rea de superf\u00edcie corporal. A maioria dos casos ocorre nas primeiras 8 semanas de exposi\u00e7\u00e3o ao medicamento. Os medicamentos mais frequentemente envolvidos s\u00e3o antimicrobianos tipo sulfonamidas, anticonvulsivantes, alopurinol, nevirapina e anti-inflamat\u00f3rios n\u00e3o esteroidais do tipo oxicans."},"en":{"language":"en","value":"This is one of the four principal forms of severe cutaneous adverse reaction to drugs (SCARs) and is characterised by inflammation, blistering and erosion of skin and mucous membranes. By definition, there is involvement of at least one mucous membrane and skin detachment is limited to less than 10% of body surface area. Most cases occur within the first 8 weeks of drug exposure. The drugs most commonly involved are antimicrobial sulfonamides, anticonvulsants, allopurinol, nevirapine and oxicam\u2013nonsteroidal anti-inflammatory drugs."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"e899620fe4b356edd217d2f031f995de01ae186f","datavalue":{"value":"https://id.who.int/icd/entity/1970262645","type":"string"},"datatype":"url"},"type":"statement","id":"Q43853$E79C0807-44C7-4B5C-BD6C-F455306B9E96","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"c9a06728ba90847462ab941b18f706210b572b03","datavalue":{"value":"CID11:EH63.0","type":"string"},"datatype":"string"},"type":"statement","id":"Q43853$A62F3226-86D5-438B-9965-1B88153902F8","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"d5f466158ab7d0ad3aaa28930a69e46ff5f3c017","datavalue":{"value":"dki-india-EH63.0","type":"string"},"datatype":"string"},"type":"statement","id":"Q43853$24B73F43-6F36-4CDA-B29A-DF189E961461","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q43853$B72CEB40-CD97-453A-BF0F-A267A891DC40","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q43853$758AECE5-0E45-47EC-B9F7-4B31DB9662E8","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q43853$9C1759F1-54EE-44AF-9942-EF2CC16B69A2","rank":"normal"}],"P89":[{"mainsnak":{"snaktype":"value","property":"P89","hash":"6e60583f34840ead9918a6809e8ee254ec992e49","datavalue":{"value":{"entity-type":"item","numeric-id":19419,"id":"Q19419"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q43853$AFA58E82-3A49-442B-9FB6-E00F2B720C11","rank":"normal"}]},"sitelinks":{}}}}