{"entities":{"Q39980":{"pageid":30348,"ns":120,"title":"Item:Q39980","lastrevid":125520,"modified":"2026-08-13T05:36:42Z","type":"item","id":"Q39980","labels":{"mul":{"language":"mul","value":"5B91.5"},"pt-br":{"language":"pt-br","value":"Excesso de mangan\u00eas"},"en":{"language":"en","value":"Manganese excess"}},"descriptions":{"pt-br":{"language":"pt-br","value":"A toxicidade do mangan\u00eas em humanos \u00e9 um risco ocupacional bem conhecido para pessoas que inalam o p\u00f3 de mangan\u00eas. Altas concentra\u00e7\u00f5es de mangan\u00eas circulante como resultado da nutri\u00e7\u00e3o parenteral total tamb\u00e9m foram associadas \u00e0 toxicidade do mangan\u00eas. Pessoas com doen\u00e7a hep\u00e1tica cr\u00f4nica t\u00eam patologia neurol\u00f3gica e sinais comportamentais de neurotoxicidade do mangan\u00eas, provavelmente porque a elimina\u00e7\u00e3o do mangan\u00eas na bile est\u00e1 prejudicada. O efeito mais proeminente \u00e9 a patologia do sistema nervoso central, especialmente no sistema motor extrapiramidal. As les\u00f5es e sintomas s\u00e3o semelhantes aos da doen\u00e7a de Parkinson."},"en":{"language":"en","value":"Manganese toxicity in humans is a well-recognised occupational hazard for people who inhale manganese dust. High concentrations of circulating manganese as a result of total parenteral nutrition have also been associated with manganese toxicity. People with chronic liver disease have neurological pathology and behavioural signs of manganese neurotoxicity, probably because elimination of manganese in bile is impaired. The most prominent effect is central nervous system pathology, especially in the extra-pyramidal motor system. The lesions and symptoms are similar to those of Parkinson\u2019s disease."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"0c8e00a6059225a8e2cb39e4b862229b729e5a00","datavalue":{"value":"https://id.who.int/icd/entity/1366519621","type":"string"},"datatype":"url"},"type":"statement","id":"Q39980$CF79003F-CA3F-4C6D-90FB-E86B4FDDD7A6","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"202feabdc2c5c9e9ab2d4abbaf03c40e8e70b317","datavalue":{"value":"CID11:5B91.5","type":"string"},"datatype":"string"},"type":"statement","id":"Q39980$24051B75-2A47-47AD-A90E-90CAC5918C84","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"f41d80f7d74c3aed3277ee6322700126eab18c34","datavalue":{"value":"dki-india-5B91.5","type":"string"},"datatype":"string"},"type":"statement","id":"Q39980$A11644C5-F384-4079-9863-D701967A8AF9","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q39980$01871E99-C89F-464B-A3DE-68F7D4FEC26B","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q39980$7CF8EDCE-541D-42FC-BAFC-8141F4CCE9A3","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q39980$21D39AA3-7477-4B69-A2B4-D8299B710EA2","rank":"normal"}],"P89":[{"mainsnak":{"snaktype":"value","property":"P89","hash":"288126a1bcc61066f06a187d8f070284c8360762","datavalue":{"value":{"entity-type":"item","numeric-id":15542,"id":"Q15542"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q39980$A4A43132-73F3-43B7-96D2-3EF807044DB5","rank":"normal"}]},"sitelinks":{}}}}