{"entities":{"Q39843":{"pageid":30211,"ns":120,"title":"Item:Q39843","lastrevid":124235,"modified":"2026-08-13T05:24:16Z","type":"item","id":"Q39843","labels":{"mul":{"language":"mul","value":"5A60.2"},"pt-br":{"language":"pt-br","value":"S\u00edndrome da secre\u00e7\u00e3o inapropriada do horm\u00f4nio antidiur\u00e9tico"},"en":{"language":"en","value":"Syndrome of inappropriate secretion of antidiuretic hormone"}},"descriptions":{"pt-br":{"language":"pt-br","value":"S\u00edndrome da secre\u00e7\u00e3o inapropriada do horm\u00f4nio antidiur\u00e9tico (ADH)- SIADH- \u00e9 caracterizada pela secre\u00e7\u00e3o cont\u00ednua de ADH causando hiponatremia, hiposmolalidade e natriurese. A prevel\u00eancia exata \u00e9 desconhecida. A doen\u00e7a tem sido descrita em grupos de todas as idades. SIADH \u00e9 frequentemente associada a tumores, doen\u00e7as pulmonares, transtornos do sistema nervoso central ou exposi\u00e7\u00e3o a drogas. Ocasionalmente ela \u00e9 encontrada em pacientes com insufici\u00eancia adrenal, tireoidiana ou hipofis\u00e1ria. O transtorno \u00e9 causado por muta\u00e7\u00f5es com ganho de fun\u00e7\u00e3o em genes que codificam o receptor de vasopressina V2. Restri\u00e7\u00e3o h\u00eddrica \u00e9 o tratamento mais comum. O resultado est\u00e1 relacionado aos dist\u00farbios subjacentes e associados."},"en":{"language":"en","value":"Syndrome of inappropriate antidiuretic hormone (ADH) secretion (SIADH) is characterised by continued ADH secretion, leading to hyponatremia, hypoosmolality and natriuresis. Exact prevalence is unknown. The disease has been described in all age groups. SIADH is often associated with tumours, pulmonary disease, central nervous system disorders or exposure to drugs. Occasionally, it is found in patients with adrenal, thyroid or pituitary insufficiency. The disorder is caused by gain-of-function mutations in the gene encoding the vasopressin V2 receptor. Fluid restriction is the most common treatment. The outcome is related to the underlying and associated disorders."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"712de77d096e3e2cfd44ac0101068a5397328d5c","datavalue":{"value":"https://id.who.int/icd/entity/550787432","type":"string"},"datatype":"url"},"type":"statement","id":"Q39843$B71094D9-5852-4723-895E-5656D6D44892","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"b66b629a464c1ebbc2e54c573bb1e91e998d4879","datavalue":{"value":"CID11:5A60.2","type":"string"},"datatype":"string"},"type":"statement","id":"Q39843$1AD0D81E-8AD9-42BA-ABD9-DA4848C6EE38","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"e19892a733252871ce398187b293f90515261d43","datavalue":{"value":"dki-india-5A60.2","type":"string"},"datatype":"string"},"type":"statement","id":"Q39843$A57AB4A4-3970-4C6C-9A51-25663D28F019","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q39843$E8BF71B0-82D1-4082-B4D1-C7EFFEA7FA6D","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q39843$84C07D85-CC3D-4712-A895-C4DFC84306A1","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q39843$D42D54FD-98B2-40E6-9298-AB593C96F516","rank":"normal"}],"P89":[{"mainsnak":{"snaktype":"value","property":"P89","hash":"41152660d49b078bc76f835488697bafaa8bf7a0","datavalue":{"value":{"entity-type":"item","numeric-id":15231,"id":"Q15231"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q39843$FAFBAF97-D1A1-46E0-984C-D2DEF2DF6409","rank":"normal"}]},"sitelinks":{}}}}