{"entities":{"Q39674":{"pageid":30042,"ns":120,"title":"Item:Q39674","lastrevid":122788,"modified":"2026-08-13T05:11:03Z","type":"item","id":"Q39674","labels":{"mul":{"language":"mul","value":"3A92"},"pt-br":{"language":"pt-br","value":"Metemoglobinemia heredit\u00e1ria"},"en":{"language":"en","value":"Hereditary methaemoglobinaemia"}},"descriptions":{"pt-br":{"language":"pt-br","value":"Metemoglobinemia heredit\u00e1ria \u00e9 um transtorno raro da hem\u00e1cia classificada principalmente em dois fen\u00f3tipos cl\u00ednicos: metemoglobinemia cong\u00eanita autoss\u00f4mica recessiva (ou heredit\u00e1ria) tipos I e II (RCM/RHM tipo I; RCM/RHM tipo 2). Na RCM tipo 1, cianose bem tolerada desde o nascimento \u00e9 o \u00fanico sintoma. RCM tipo 2, com perda global da fun\u00e7\u00e3o do Cb5R, \u00e9 muito mais grave; a cianose \u00e9 acompanhada por disfun\u00e7\u00e3o neurol\u00f3gica (com d\u00e9ficit intelectual, microcefalia, retardo do crescimento, opist\u00f3tono, estrabismo e hipertonia), que geralmente se torna evidente durante os primeiros quatro meses de vida."},"en":{"language":"en","value":"Hereditary methemoglobinemia (HM) is a rare red cell disorder classified principally into two clinical phenotypes: autosomal recessive congenital (or hereditary) methemoglobinemia types I and II (RCM/RHM type 1; RCM/RHM type 2). In RCM type 1, well-tolerated cyanosis from birth is the only symptom. RCM type 2, with global loss of Cb5R function, is much more severe; the cyanosis is accompanied by neurological dysfunction (with intellectual deficit, microcephaly, growth retardation, opisthotonus, strabismus and hypertonia), which usually becomes evident during the first four months of life."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"0b35a3f0ca4782d25297eb4d1116f860bc6c4138","datavalue":{"value":"https://id.who.int/icd/entity/586921197","type":"string"},"datatype":"url"},"type":"statement","id":"Q39674$3584BF85-32D9-4439-9CFB-FACC3E08323F","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"e87f2ecc2919e420bdf8590e58fbbe7f203f1a43","datavalue":{"value":"CID11:3A92","type":"string"},"datatype":"string"},"type":"statement","id":"Q39674$DF2710BB-2986-42A3-991C-23F51F00F11C","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"f7a116b700fc4272fb8a01468a6b3bb55c6e6255","datavalue":{"value":"dki-india-3A92","type":"string"},"datatype":"string"},"type":"statement","id":"Q39674$32331310-675D-46FC-8B12-78C65A6C04F4","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q39674$CD7A3E11-8FDE-4FC4-AE2B-7FAC07B22655","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q39674$906B2114-DEC8-4EF8-9228-BC18D2772B7E","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q39674$7101F661-3694-4640-AA70-26507376E7A3","rank":"normal"}],"P89":[{"mainsnak":{"snaktype":"value","property":"P89","hash":"f913f2b77699c9a2b972cc9674154619ae3e5616","datavalue":{"value":{"entity-type":"item","numeric-id":14843,"id":"Q14843"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q39674$B91D1529-4033-4A9E-B7F8-B26251CBE8EF","rank":"normal"}]},"sitelinks":{}}}}